Cell biology of the osteoclast (Q33700885)

28 July 2017

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title

Cell biology of the osteoclast (English)

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28 July 2017

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Roodman GD

1

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28 July 2017

publication date

1 August 1999

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28 July 2017

published in

Experimental Hematology

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28 July 2017

volume

27

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28 July 2017

issue

8

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28 July 2017

page(s)

1229-1241

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In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes

28 July 2017

cites work

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7 January 2021

Identification of committed mononuclear precursors for osteoclast-like cells formed in long term human marrow cultures

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7 January 2021

Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.

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7 January 2021

Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitonin

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7 January 2021

Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cells

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7 January 2021

Calcitonin receptor isoforms in mouse and rat osteoclasts

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7 January 2021

Isolation and Characterization of Highly Enriched, Prefusion Mouse Osteoclastic Cells

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7 January 2021

Isolated osteoclasts and their presumed progenitor cells, the monocyte, in culture

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7 January 2021

Isolated osteoclasts in primary culture: first observations on structure and survival in culture media.

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7 January 2021

Use of an in vivo model to determine the effects of interleukin-1 on cells at different stages in the osteoclast lineage

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7 January 2021

Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells

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7 January 2021

Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures

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7 January 2021

1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures

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7 January 2021

1,25(OH)2D3 induces differentiation of osteoclast-like cells from human bone marrow cultures.

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7 January 2021

Formation of osteoclasts and osteoblast-like cells in long-term human bone marrow cultures.

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7 January 2021

The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells

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7 January 2021

Preparation and characterization of a mouse osteoclast-like multinucleated cell population.

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7 January 2021

New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro

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7 January 2021

Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice

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7 January 2021

Generation of mouse osteoclastogenic cell lines immortalized with SV40 large T antigen

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7 January 2021

Osteoblastic cells are involved in osteoclast formation.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells

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7 January 2021

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoprotegerin and its cognate ligand: a new paradigm of osteoclastogenesis

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Two squamous cell carcinomas not associated with humoral hypercalcemia produce a potent bone resorption-stimulating factor which is interleukin-1 alpha

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Parathyroid hormone-related protein and interleukin-1 alpha synergistically stimulate bone resorption in vitro and increase the serum calcium concentration in mice in vivo

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Macrophage colony-stimulating factor release and receptor expression in bone cells

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Expression of human transforming growth factor alpha by Chinese hamster ovarian tumors in nude mice causes hypercalcemia and increased osteoclastic bone resorption

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures

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7 January 2021

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts

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7 January 2021

Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells

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7 January 2021

Evidence that tumor necrosis factor plays a pathogenetic role in the paraneoplastic syndromes of cachexia, hypercalcemia, and leukocytosis in a human tumor in nude mice

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7 January 2021

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

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7 January 2021

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone

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7 January 2021

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-11: a new cytokine critical for osteoclast development

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Inhibiting and stimulating effects of TGF-beta 1 on osteoclastic bone resorption in fetal mouse bone organ cultures

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Ovariectomy decreases the mRNA levels of transforming growth factor-beta 1 and increases the mRNA levels of osteocalcin in rat bone in vivo

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Comparative study of inhibitory effects by murine interferon ? and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK)

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-4 as a potent inhibitor of bone resorption

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-4 modulates osteoclast differentiation and inhibits the formation of resorption pits in mouse osteoclast cultures

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-4 inhibits spontaneous and parathyroid hormone-related protein-stimulated osteoclast formation in mice.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoporosis induced in mice by overproduction of interleukin 4.

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Inducible production of nitric oxide in osteoblast-like cells and in fetal mouse bone explants is associated with suppression of osteoclastic bone resorption

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Human giant cell tumors of the bone (osteoclastomas) are estrogen target cells

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Avian osteoclasts as estrogen target cells

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin 18 inhibits osteoclast formation via T cell production of granulocyte macrophage colony-stimulating factor.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone-resorbing activity of isolated mature osteoclasts.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

A synthetic analogue of vitamin D3, 22-oxa-1 alpha,25-dihydroxyvitamin D3, is a potent modulator of in vivo immunoregulating activity without inducing hypercalcemia in mice

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Interleukin-6 is produced by bone and modulated by parathyroid hormone

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Role of osteoblasts in hormonal control of bone resorption—A hypothesis

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoblastic cells mediate osteoclastic responsiveness to parathyroid hormone

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transduction

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Prostaglandin E2 inhibits formation of osteoclastlike cells in long-term human marrow cultures but is not a mediator of the inhibitory effects of transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Inhibitory and stimulatory effects of prostaglandins on osteoclast differentiation

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoclast synthesis and secretion and activation of latent transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Characterization of the osteoclast vacuolar H -ATPase B-subunit

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteoclastic bone resorption by a polarized vacuolar proton pump

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src-/- mutant mice

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Substrate recognition by osteoclast precursors induces C-src/microtubule association.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Humoral and ionic regulation of osteoclast acidity

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Ultrastructural immunocytochemical localization of carbonic anhydrase in normal and calcitonin-treated chick osteoclasts

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Carbonic anhydrase II deficiency in 12 families with the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification

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https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Carbonic anhydrase and bone remodeling: sulfonamide inhibition of bone resorption in organ culture

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Transforming growth factor-beta 1 as a signal for induction of cell death by apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016/S0301-472X(99)50061-2

7 January 2021

10.1016/S0301-472X(99)00061-2

Identifiers

DOI

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28 July 2017

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