Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteers (Q33700538)

28 July 2017

title

Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteers (English)

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28 July 2017

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A Hsu

1

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28 July 2017

G R Granneman

2

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28 July 2017

G Cao

3

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28 July 2017

L Carothers

4

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28 July 2017

A Japour

5

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28 July 2017

T El-Shourbagy

6

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28 July 2017

S Dennis

7

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28 July 2017

J Berg

8

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28 July 2017

K Erdman

9

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28 July 2017

J M Leonard

10

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28 July 2017

E Sun

11

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28 July 2017

language of work or name

English

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publication date

1 November 1998

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Antimicrobial Agents and Chemotherapy

28 July 2017

published in

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28 July 2017

volume

42

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28 July 2017

issue

11

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28 July 2017

page(s)

2784-2791

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HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

28 July 2017

cites work

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Single-dose pharmacokinetics of indinavir and the effect of food.

21 June 2018

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The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

21 June 2018

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Urolithiasis associated with the protease inhibitor indinavir

21 June 2018

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Crystalluria and urinary tract abnormalities associated with indinavir

21 June 2018

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21 June 2018

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Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 June 2018

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Multiple-dose pharmacokinetics of ritonavir in human immunodeficiency virus-infected subjects

21 June 2018

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Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

21 June 2018

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21 June 2018

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First-pass metabolism of midazolam by the human intestine.

21 June 2018

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The effect of high-dose saquinavir on viral load and CD4 T-cell counts in HIV-infected patients.

21 June 2018

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Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

21 June 2018

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

21 June 2018

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Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: application to acute retroviral infection.

21 June 2018

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CYP3A gene expression in human gut epithelium

21 June 2018

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 June 2018

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ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans

21 June 2018

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Rapid and Precise Quantification of HIV-1 RNA in Plasma Using a Branched DNA Signal Amplification Assay

21 June 2018

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pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs

21 June 2018

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A short-term study of the safety, pharmacokinetics, and efficacy of ritonavir, an inhibitor of HIV-1 protease. European-Australian Collaborative Ritonavir Study Group

21 June 2018

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Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

21 June 2018

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Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 June 2018

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Time-course of interaction between carbamazepine and clonazepam in normal man

21 June 2018

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Pharmacokinetic interactions between two human immunodeficiency virus protease inhibitors, ritonavir and saquinavir

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108634

Protease inhibitor-induced urolithiasis

30 October 2018

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Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor.

30 October 2018

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First-pass metabolism of cyclosporin by the gut

30 October 2018

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12 December 2020

Regiospecific intestinal absorption of the HIV protease inhibitor L-735,524 in beagle dogs

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12 December 2020

Delta: a randomised double-blind controlled trial comparing combinations of zidovudine plus didanosine or zalcitabine with zidovudine alone in HIV-infected individuals. Delta Coordinating Committee

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Disposition of indinavir, a potent HIV-1 protease inhibitor, after an oral dose in humans

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12 December 2020

Determination of ritonavir, a new HIV protease inhibitor, in biological samples using reversed-phase high-performance liquid chromatography

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12 December 2020

Recent developments in HIV protease inhibitor therapy

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12 December 2020

Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: the CAESAR trial

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12 December 2020

Identifiers

DOI

10.1128/AAC.42.11.2784

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PMC publication ID

108634

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28 July 2017

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