Aging of the innate immune system (Q33666891)

28 July 2017

1 reference

title

Aging of the innate immune system (English)

1 reference

28 July 2017

Janet M Lord

5

0 references

author name string

Albert C Shaw

1

1 reference

28 July 2017

Samit Joshi

2

1 reference

28 July 2017

Hannah Greenwood

3

1 reference

28 July 2017

Alexander Panda

4

1 reference

28 July 2017

publication date

1 August 2010

1 reference

Current Opinion in Immunology

28 July 2017

published in

1 reference

28 July 2017

volume

22

1 reference

28 July 2017

issue

4

1 reference

28 July 2017

page(s)

507-513

1 reference

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Dehydroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Dehydroepiandrosterone as a regulator of immune cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Impaired immune responses in the lungs of aged mice following influenza infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Human innate immunosenescence: causes and consequences for immunity in old age.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

NK cells in the CD19- B220 bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

NK and NKT cells in aging and longevity: role of zinc and metallothioneins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Effects of aging on the immunopathologic response to sepsis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging impairs IFN regulatory factor 7 up-regulation in plasmacytoid dendritic cells during TLR9 activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging augments IL-17 T-cell alloimmune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Comparison of the effects of aging and IL-6 on the hepatic inflammatory response in two models of systemic injury: scald injury versus i.p. LPS administration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Innate immunity and aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Signal transduction and functional changes in neutrophils with aging.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Follicular dendritic cells in aging, a "bottle-neck" in the humoral immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Neutrophil extracellular traps kill bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Immunosenescence of polymorphonuclear neutrophils.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4 T cells during aging

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies I.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Modulation of CXC chemokine receptor expression and function in human neutrophils during aging in vitro suggests a role in their clearance from circulation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Impaired dendritic cell function in aging leads to defective antitumor immunity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of 647 MT1a and -174 IL-6 polymorphic alleles

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Advanced age exacerbates the pulmonary inflammatory response after lipopolysaccharide exposure.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Molecular basis of age-associated cytokine dysregulation in LPS-stimulated macrophages

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Raised cortisol:DHEAS ratios in the elderly after injury: potential impact upon neutrophil function and immunity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Age-associated augmentation of the synthetic ligand- mediated function of mouse NK1.1 ag( ) T cells: their cytokine production and hepatotoxicity in vivo and in vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034446

Age-associated defect in human TLR-1/2 function

30 October 2018

1 reference

12 December 2020

Peripheral blood dendritic cells and monocytes are differently regulated in the elderly

1 reference

12 December 2020

Prevaccine Determination of the Expression of Costimulatory B7 Molecules in Activated Monocytes Predicts Influenza Vaccine Responses in Young and Older Adults

1 reference

12 December 2020

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition

1 reference

12 December 2020

Functional alterations of liver innate immunity of mice with aging in response to CpG-oligodeoxynucleotide

1 reference

12 December 2020

Telomere Shortening and Oxidative Stress in Aged Macrophages Results in Impaired STAT5a Phosphorylation

1 reference

12 December 2020

Effect of age on human neutrophil function

1 reference

12 December 2020

Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans

1 reference

12 December 2020

Cutting edge: impaired Toll-like receptor expression and function in aging

1 reference

12 December 2020

Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression

1 reference

12 December 2020

The unresponsiveness of aged mice to polysaccharide antigens is a result of a defect in macrophage function

1 reference

12 December 2020

CD1d-restricted NKT cells contribute to the age-associated decline of T cell immunity

1 reference

12 December 2020

Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway

1 reference

12 December 2020

Effect of aging on bone marrow-derived murine CD11c CD4-CD8alpha- dendritic cell function

1 reference

12 December 2020

Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging

1 reference

12 December 2020

10.1016/J.COI.2010.05.003

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference