Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis (Q33653056)

28 July 2017

title

Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis (English)

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28 July 2017

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African trypanosomiasis

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Alan H Fairlamb

6

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Laste Stojanovski

series ordinal

3

object named as

Laste Stojanovski

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28 July 2017

4

Kevin D Read

1 reference

28 July 2017

2

Irene Hallyburton

1 reference

28 July 2017

5

Julie A Frearson

1 reference

28 July 2017

1

Deuan C Jones

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28 July 2017

language of work or name

English

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publication date

7 August 2010

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28 July 2017

published in

Biochemical Pharmacology

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28 July 2017

volume

80

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28 July 2017

issue

10

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28 July 2017

page(s)

1478-1486

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Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis

28 July 2017

cites work

1 reference

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21 June 2018

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21 June 2018

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21 June 2018

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Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes

21 June 2018

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21 June 2018

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A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker

21 June 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 June 2018

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The Alamar Blue® assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

21 June 2018

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The treatment of human African trypanosomiasis

21 June 2018

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21 June 2018

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Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro

21 June 2018

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21 June 2018

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Physiological activation of the mitochondrion and the transformation capacity of DFMO induced intermediate and short stumpy bloodstream form trypanosomes.

21 June 2018

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21 June 2018

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Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis

21 June 2018

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Comparison of the in vitro drug sensitivity of Trypanosoma brucei gambiense strains from West and Central Africa isolated in the periods 1960-1995 and 1999-2004.

30 October 2018

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Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei

30 October 2018

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30 October 2018

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30 October 2018

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U-50,488: a selective and structurally novel non-Mu (kappa) opioid agonist

30 October 2018

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Antibiotics as tools for metabolic studies. I. A survey of toxic antibiotics in respiratory, phosphorylative and glycolytic systems

30 October 2018

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCP.2010.07.038

1 reference

28 July 2017

1 reference

28 July 2017

1 reference