The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants. (Q33651140)

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9 February 2020

title

The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants (English)

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3

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Irini Sereti

9

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6

Joseph W Adelsberger

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author name string

Sarah W Read

1

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9 February 2020

Mary DeGrezia

2

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Rebecca DerSimonian

4

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9 February 2020

Jeanette Higgins

5

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Judith M Starling

7

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9 February 2020

Catherine Rehm

8

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language of work or name

English

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publication date

3 August 2010

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volume

5

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issue

8

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page(s)

e11937

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Creative Commons CC0 License

9 February 2020

copyright license

start time

3 August 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

Lessons learned from the natural hosts of HIV-related viruses

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21 June 2018

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Collagen deposition limits immune reconstitution in the gut

21 June 2018

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Role of immune activation in HIV pathogenesis

21 June 2018

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Human immunodeficiency virus-like particles activate multiple types of immune cells.

21 June 2018

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

21 June 2018

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Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4 T cells in human immunodeficiency virus type 1 infection.

21 June 2018

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A prospective evaluation of leflunomide therapy for cytomegalovirus disease in renal transplant recipients

21 June 2018

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Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

21 June 2018

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Regulation of TNF-related apoptosis-inducing ligand on primary CD4 T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells

21 June 2018

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Population pharmacokinetics and association between A77 1726 plasma concentrations and disease activity measures following administration of leflunomide to people with rheumatoid arthritis

21 June 2018

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Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis.

21 June 2018

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Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

21 June 2018

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Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4 and CD8 T cell turnover in HIV-infected patients

21 June 2018

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Mechanisms of HIV-associated lymphocyte apoptosis

21 June 2018

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Mechanism of action of leflunomide in rheumatoid arthritis.

21 June 2018

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CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

21 June 2018

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Engagement of adhesion molecules (CD18, CD11a, CD45, CD44, and CD58) enhances human immunodeficiency virus type 1 replication in monocytic cells through a tumor necrosis factor-modulated pathway

21 June 2018

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Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

21 June 2018

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The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.

21 June 2018

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CD8 T-lymphocyte activation in HIV-1 disease reflects an aspect of pathogenesis distinct from viral burden and immunodeficiency

21 June 2018

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Incomplete CD4 T cell recovery in HIV-1 infection after 12 months of highly active antiretroviral therapy is associated with ongoing increased CD4 T cell activation and turnover

21 January 2018

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Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia

21 January 2018

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A pilot study of the use of mycophenolate mofetil as a component of therapy for multidrug-resistant HIV-1 infection

21 January 2018

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The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA.

21 January 2018

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Cyclosporin A Provides No Sustained Immunologic Benefit to Persons with Chronic HIV‐1 Infection Starting Suppressive Antiretroviral Therapy: Results of a Randomized, Controlled Trial of the AIDS Clinical Trials Group A5138

21 January 2018

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Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides

21 January 2018

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Treatment of renal allograft polyoma BK virus infection with leflunomide

21 January 2018

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Anti-HIV-1 activity of leflunomide: a comparison with mycophenolic acid and hydroxyurea

21 January 2018

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A real-time TaqMan PCR for routine quantitation of cytomegalovirus DNA in crude leukocyte lysates from stem cell transplant patients

21 January 2018

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Inhibition of HIV Replication by A77 1726, the Active Metabolite of Leflunomide, in Combination With Pyrimidine Nucleoside Reverse Transcriptase Inhibitors

21 January 2018

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Inhibition of HIV replication by A77 1726, the active metabolite of leflunomide, in combination with pyrimidine nucleoside reverse transcriptase inhibitors

21 January 2018

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CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients

30 October 2018

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12 December 2020

Anti-HIV activity of the combination of didanosine and hydroxyurea in HIV-1-infected individuals

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12 December 2020

Hydroxyurea treatment in HIV-infected patients

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12 December 2020

Elevated CD38 antigen expression on CD8 T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4 cell count, soluble immune activation markers, or combinations of

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12 December 2020

Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count

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12 December 2020

10.1371/JOURNAL.PONE.0011937

Identifiers

DOI

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9 February 2020

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9 February 2020

PubMed publication ID

20689824

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