Quantitative and molecular genetic analyses of mutations increasing Drosophila life span (Q33649850)

28 July 2017

title

Quantitative and molecular genetic analyses of mutations increasing Drosophila life span (English)

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28 July 2017

1 reference

8

Trudy F C Mackay

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28 July 2017

3

Mary Anna Carbone

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28 July 2017

Michael M Magwire

1

1 reference

28 July 2017

Akihiko Yamamoto

2

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28 July 2017

Natalia V Roshina

4

1 reference

28 July 2017

Alexander V Symonenko

5

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28 July 2017

Elena G Pasyukova

6

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28 July 2017

Tatiana V Morozova

7

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28 July 2017

language of work or name

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29 July 2010

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28 July 2017

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28 July 2017

volume

6

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28 July 2017

issue

7

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28 July 2017

page(s)

e1001037

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

29 July 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Lifespan regulation by evolutionarily conserved genes essential for viability

14 July 2018

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Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster

14 July 2018

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New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen

14 July 2018

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A systematic RNAi screen for longevity genes in C. elegans

14 July 2018

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Age-specific changes in epistatic effects on mortality rate in Drosophila melanogaster.

14 July 2018

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Age-dependent changes of gene expression in the Drosophila head

14 July 2018

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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

14 July 2018

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Sex-specific effects of interventions that extend fly life span.

14 July 2018

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The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

14 July 2018

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

14 July 2018

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14 July 2018

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Quantitative trait loci affecting starvation resistance in Drosophila melanogaster

14 July 2018

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Comparing genomic expression patterns across species identifies shared transcriptional profile in aging

14 July 2018

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Prolongation of the life of Drosophila subobscura by a brief exposure of adults to a high temperature

14 July 2018

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Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones

14 July 2018

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Statistical significance for genomewide studies

14 July 2018

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Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background

14 July 2018

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Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

14 July 2018

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Expression of Drosophila FOXO regulates growth and can phenocopy starvation

14 July 2018

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Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

14 July 2018

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A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

The endocrine regulation of aging by insulin-like signals

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

14 July 2018

1 reference

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A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

The complex genetic architecture of Drosophila life span

14 July 2018

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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Genome-wide study of aging and oxidative stress response in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Quantitative trait loci for life span in Drosophila melanogaster: interactions with genetic background and larval density

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Insertion site preferences of the P transposable element in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Gene expression profile of aging and its retardation by caloric restriction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Extended life-span and stress resistance in the Drosophila mutant methuselah

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

The genetics of caloric restriction in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Epistatic interactions between smell-impaired loci in Drosophila melanogaster.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Dwarf mice and the ageing process.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Age-specific patterns of genetic variance in Drosophila melanogaster. II. Fecundity and its genetic covariance with age-specific mortality

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A C. elegans mutant that lives twice as long as wild type

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

The effects of spontaneous mutation on quantitative traits. I. Variances and covariances of life history traits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Genetics of life history in Drosophila melanogaster. I. Sib analysis of adult females.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A test of evolutionary theories of senescence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Genetic differences in effects of food restriction on aging in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Selection on stress resistance increases longevity in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

Pleiotropy, Natural Selection, and the Evolution of Senescence

14 July 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Long-lived Drosophila with overexpressed dFOXO in adult fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Stress resistance and longevity in selected lines of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Probing the evolution of senescence in Drosophila melanogaster with P-element tagging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Extended life-span conferred by cotransporter gene mutations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Steroid control of longevity in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Regulation of Drosophila life span by olfaction and food-derived odors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Sex differences in the effect of dietary restriction on life span and mortality rates in female and male Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

SELECTION FOR DELAYED SENESCENCE IN DROSOPHILA MELANOGASTER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

DIRECT SELECTION ON LIFE SPAN IN DROSOPHILA MELANOGASTER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Laboratory Evolution of Postponed Senescence in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912381

A cost of mating in female fruitflies

30 October 2018

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PGEN.1001037

DIRECT AND CORRELATED RESPONSES TO SELECTION ON AGE AT REPRODUCTION IN DROSOPHILA MELANOGASTER

21 January 2018

1 reference

12 December 2020

THE EVOLUTIONARY GENETICS OF MALE LIFE-HISTORY CHARACTERS IN DROSOPHILA MELANOGASTER

1 reference

12 December 2020

EVOLUTIONARY EFFECTS OF SELECTION ON AGE AT REPRODUCTION IN LARVAL AND ADULT: DROSOPHILA MELANOGASTER.

1 reference

12 December 2020

Direct isolation of longevity mutants in the nematodeCaenorhabditis elegans

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1001037

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference