Monitoring drug-induced gammaH2AX as a pharmacodynamic biomarker in individual circulating tumor cells (Q33638864)

28 July 2017

title

Monitoring drug-induced gammaH2AX as a pharmacodynamic biomarker in individual circulating tumor cells (English)

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28 July 2017

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Lihua H Wang

1

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28 July 2017

Thomas D Pfister

2

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28 July 2017

Ralph E Parchment

3

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28 July 2017

Shivaani Kummar

4

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28 July 2017

Larry Rubinstein

5

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28 July 2017

Yvonne A Evrard

6

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28 July 2017

Martin E Gutierrez

7

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28 July 2017

Anthony J Murgo

8

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28 July 2017

Joseph E Tomaszewski

9

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28 July 2017

James H Doroshow

10

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28 July 2017

Robert J Kinders

11

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28 July 2017

language of work or name

English

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publication date

26 January 2010

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28 July 2017

published in

Clinical Cancer Research

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28 July 2017

volume

16

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28 July 2017

issue

3

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28 July 2017

page(s)

1073-1084

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Gene expression of circulating tumour cells and its correlation with tumour stage in breast cancer patients.

28 July 2017

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21 June 2018

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Circulating tumor cells and bone marrow micrometastasis

21 June 2018

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21 June 2018

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21 June 2018

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Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy.

21 June 2018

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Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase

21 June 2018

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The prognostic implications of circulating tumor cells in patients with breast cancer

21 June 2018

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Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters

21 June 2018

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American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

21 June 2018

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Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents

21 June 2018

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An optimized method for detecting gamma-H2AX in blood cells reveals a significant interindividual variation in the gamma-H2AX response among humans

21 June 2018

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Topoisomerase I inhibitors: camptothecins and beyond

21 June 2018

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 June 2018

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Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer

21 June 2018

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ATM signaling and genomic stability in response to DNA damage

21 June 2018

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Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases

21 June 2018

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Circulating tumor cells, disease progression, and survival in metastatic breast cancer

21 June 2018

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HER-2 gene amplification can be acquired as breast cancer progresses

21 June 2018

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Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin

21 June 2018

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Histone H2A variants H2AX and H2AZ

21 June 2018

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 June 2018

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Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

21 June 2018

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An overview of cyclophosphamide development and clinical applications.

21 June 2018

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Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors.

21 June 2018

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HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer

30 October 2018

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Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.

30 October 2018

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Are we taking without giving in return? The ethics of research-related biopsies and the benefits of clinical trial participation

30 October 2018

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Global gene expression profiling of circulating endothelial cells in patients with metastatic carcinomas.

30 October 2018

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Global gene expression profiling of circulating tumor cells.

30 October 2018

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Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation.

30 October 2018

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Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells

30 October 2018

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The comet assay in clinical practice

30 October 2018

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12 December 2020

Circulating tumor cells in patients with breast cancer dormancy

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12 December 2020

Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival

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12 December 2020

Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer

1 reference

12 December 2020

10.1158/1078-0432.CCR-09-2799

Identifiers

DOI

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28 July 2017

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28 July 2017

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