Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation (Q33632763)

28 July 2017

title

Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation (English)

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28 July 2017

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11

Dieter Steinhilber

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28 July 2017

Khader Awwad

1

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28 July 2017

Svenja D Steinbrink

2

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28 July 2017

Timo Frömel

3

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28 July 2017

Nicole Lill

4

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28 July 2017

Johann Isaak

5

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28 July 2017

Ann-Kathrin Häfner

6

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28 July 2017

Jessica Roos

7

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28 July 2017

Bettina Hofmann

8

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28 July 2017

Heinrich Heide

9

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28 July 2017

Gerd Geisslinger

10

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28 July 2017

Bruce A Freeman

12

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28 July 2017

Thorsten J Maier

13

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28 July 2017

Ingrid Fleming

14

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28 July 2017

publication date

3 February 2014

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Antioxidants & Redox Signaling

28 July 2017

published in

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28 July 2017

volume

20

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28 July 2017

issue

17

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28 July 2017

page(s)

2667-2680

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Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase

28 July 2017

cites work

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Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416.

21 June 2018

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Dimerization of human 5-lipoxygenase

21 June 2018

1 reference

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21 June 2018

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Formation and signaling actions of electrophilic lipids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

The Structure of Human 5-Lipoxygenase

21 June 2018

1 reference

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Leukotriene B4 amplifies NF-κB activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression

21 June 2018

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21 June 2018

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The 5‐lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

21 June 2018

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Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease

21 June 2018

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Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions

21 June 2018

1 reference

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Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment

21 June 2018

1 reference

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Nitro-oleic acid protects against endotoxin-induced endotoxemia and multiorgan injury in mice

21 June 2018

1 reference

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Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid

21 June 2018

1 reference

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Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury

21 June 2018

1 reference

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LC/MS/MS analysis of leukotriene B4 and other eicosanoids in exhaled breath condensate for assessing lung inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase

21 June 2018

1 reference

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Molecular recognition of nitrated fatty acids by PPARγ

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Leukotrienes, antileukotrienes and asthma

21 June 2018

1 reference

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5-Lipoxygenase: regulation of expression and enzyme activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Therapeutic options for 5-lipoxygenase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Leukotriene modifiers as potential therapeutics for cardiovascular disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Mechanisms of signal transduction mediated by oxidized lipids: the role of the electrophile-responsive proteome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Prostaglandins and leukotrienes: advances in eicosanoid biology

21 June 2018

1 reference

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Activators and target genes of Rel/NF-kappaB transcription factors

21 June 2018

1 reference

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21 June 2018

The Protein Data Bank

1 reference

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Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Cloning of the guinea pig 5-lipoxygenase gene and nucleotide sequence of its promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Leukotriene inflammatory mediators meet their match

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

5-lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Nitro-fatty acid metabolome: saturation, desaturation, beta-oxidation, and protein adduction

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

Iron content of human 5-lipoxygenase, effects of mutations regarding conserved histidine residues.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4026401

The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24206143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of mammalian 5-lipoxygenase by aromatic disulfides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24206143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selenium-dependent peroxidases suppress 5-lipoxygenase activity in B-lymphocytes and immature myeloid cells. The presence of peroxidase-insensitive 5-lipoxygenase activity in differentiated myeloid cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24206143

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/ARS.2013.5473

1 reference

28 July 2017

1 reference

28 July 2017

1 reference