Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models. (Q33628006)

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English	Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.	scientific article

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20 March 2020

Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models (English)

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20 March 2020

prion protein family

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Syed Zahid Ali Shah

2

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20 March 2020

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Zhiqi Song

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20 March 2020

Wei Yang

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20 March 2020

Haodi Dong

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20 March 2020

Lifeng Yang

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20 March 2020

Xiangmei Zhou

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20 March 2020

Deming Zhao

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3 May 2017

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20 March 2020

Frontiers in Molecular Neuroscience

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20 March 2020

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20 March 2020

128

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20 March 2020

PRAS40 alleviates neurotoxic prion peptide-induced apoptosis via mTOR-AKT signaling.

1 reference

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21 June 2018

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413570

21 June 2018

REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling

1 reference

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21 June 2018

HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway

1 reference

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21 June 2018

Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion

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21 June 2018

Protective variant for hippocampal atrophy identified by whole exome sequencing

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21 June 2018

NRSF/REST regulates the mTOR signaling pathway in oral cancer cells

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21 June 2018

NRSF: an angel or a devil in neurogenesis and neurological diseases

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21 June 2018

Wnt signalling in neuronal differentiation and development.

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21 June 2018

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration.

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21 June 2018

Casein kinase 1 suppresses activation of REST in insulted hippocampal neurons and halts ischemia-induced neuronal death

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21 June 2018

Comparison of 2 synthetically generated recombinant prions

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21 June 2018

REST and stress resistance in ageing and Alzheimer's disease

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21 June 2018

Making new contacts: the mTOR network in metabolism and signalling crosstalk

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21 June 2018

Wnt signaling in the nervous system and in Alzheimer's disease.

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21 June 2018

Peripherally administrated prions reach the brain at sub-infectious quantities in experimental hamsters

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21 June 2018

Abnormal activation of microglia accompanied with disrupted CX3CR1/CX3CL1 pathway in the brains of the hamsters infected with scrapie agent 263K.

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21 June 2018

Molecular mechanisms of neurodegeneration mediated by dysfunctional subcellular organelles in transmissible spongiform encephalopathies

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21 June 2018

The complex world of WNT receptor signalling

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21 June 2018

Glycogen synthase kinase 3 inhibition promotes lysosomal biogenesis and autophagic degradation of the amyloid-β precursor protein

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21 June 2018

Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases

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21 June 2018

Protein localization in disease and therapy.

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21 June 2018

A signaling loop of REST, TSC2 and β-catenin governs proliferation and function of PC12 neural cells

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21 June 2018

Nuclear transport, oxidative stress, and neurodegeneration

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21 June 2018

Mest/Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5413570

21 June 2018

The intricate mechanisms of neurodegeneration in prion diseases.

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21 June 2018

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

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21 June 2018

Molecular pathology of human prion disease

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21 June 2018

Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum

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21 June 2018

Location, location, location: altered transcription factor trafficking in neurodegeneration

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21 June 2018

Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor

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21 June 2018

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

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21 June 2018

PTEN-deficient intestinal stem cells initiate intestinal polyposis

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21 June 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

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21 June 2018

Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression

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21 June 2018

mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease

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21 June 2018

Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy.

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21 June 2018

Upstream and downstream of mTOR

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21 June 2018

Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3

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21 June 2018

Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB

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CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium

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Regulation of translation initiation following stress.

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21 June 2018

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

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21 June 2018

Prion distribution in hamster lung and brain following intraperitoneal inoculation

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21 June 2018

NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis

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21 June 2018

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21 June 2018

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis

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ALCAR Exerts Neuroprotective and Pro-Neurogenic Effects by Inhibition of Glial Activation and Oxidative Stress via Activation of the Wnt/β-Catenin Signaling in Parkinsonian Rats

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21 January 2018

Overexpression of BAT3 alleviates prion protein fragment PrP106-126-induced neuronal apoptosis.

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21 January 2018

Neuronal autophagy in experimental scrapie

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12 December 2020

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10.3389/FNMOL.2017.00128

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20 March 2020

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20 March 2020

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20 March 2020

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