N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42 (Q33626314)

28 July 2017

title

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42 (English)

1 reference

28 July 2017

Carlo Sala Frigerio

6

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Georg Meisl

object named as

Georg Meisl

3

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Tuomas Knowles

object named as

Tuomas Knowles

10

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Sara Snogerup Linse

12

object named as

Sara Linse

1 reference

28 July 2017

5

Birgitta Frohm

1 reference

28 July 2017

9

Robert G Griffin

1 reference

28 July 2017

Olga Szczepankiewicz

1

1 reference

28 July 2017

Björn Linse

2

1 reference

28 July 2017

Eva Thulin

4

1 reference

28 July 2017

Michael T Colvin

7

1 reference

28 July 2017

Angela C Jacavone

8

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28 July 2017

Dominic M Walsh

11

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28 July 2017

language of work or name

English

0 references

publication date

4 November 2015

1 reference

Journal of the American Chemical Society

28 July 2017

published in

1 reference

28 July 2017

volume

137

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28 July 2017

issue

46

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28 July 2017

page(s)

14673-14685

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Molecular mechanisms of protein aggregation from global fitting of kinetic models.

28 July 2017

cites work

1 reference

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Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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From macroscopic measurements to microscopic mechanisms of protein aggregation

28 July 2018

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28 July 2018

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Functional interactions as a survival strategy against abnormal aggregation

28 July 2018

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Accelerated formation of alpha-synuclein oligomers by concerted action of the 20S proteasome and familial Parkinson mutations

28 July 2018

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28 July 2018

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28 July 2018

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Disordered flanks prevent peptide aggregation

28 July 2018

1 reference

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Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry

28 July 2018

1 reference

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Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

28 July 2018

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

28 July 2018

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Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

28 July 2018

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High resolution structural characterization of Aβ42 amyloid fibrils by magic angle spinning NMR.

28 July 2018

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30 October 2018

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Role of aromatic side chains in amyloid β-protein aggregation

30 October 2018

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Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process

30 October 2018

1 reference

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A new structural model of Aβ40 fibrils.

30 October 2018

1 reference

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Monte Carlo simulations of protein amyloid formation reveal origin of sigmoidal aggregation kinetics

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

30 October 2018

1 reference

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30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

N-terminal truncated pyroglutamyl beta amyloid peptide Abetapy3-42 shows a faster aggregation kinetics than the full-length Abeta1-42.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Prediction of aggregation-prone regions in structured proteins

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Hsp110 is a nucleotide-activated exchange factor for Hsp70.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Protein folding through kinetic discrimination

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

The N-terminal repeat domain of alpha-synuclein inhibits beta-sheet and amyloid fibril formation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

The behaviour of polyamino acids reveals an inverse side chain effect in amyloid structure formation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

A systematic exploration of the influence of the protein stability on amyloid fibril formation in vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Hypothesis: amyloid beta-peptides truncated at the N-terminus contribute to the pathogenesis of Alzheimer's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Interactions in the native state of monellin, which play a protective role against aggregation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5412961

Folding and fibril formation of the cell cycle protein Cks1

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26535489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amyloid fibril formation by circularly permuted and C-terminally deleted mutants

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26535489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26535489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JACS.5B07849

1 reference

28 July 2017

1 reference

28 July 2017

1 reference