Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction. (Q33615103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

title

Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

main subject

Lysyl-tRNA synthetase 1

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Pengfei Fang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Nicolas L. Young

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

29

Byung Woo Han

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

23

Aree Moon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Dae Gyu Kim

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jin Young Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Nam Hoon Kwon

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Qian Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jing Wang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Min Guo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Hye Young Cho

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Ameeq Ul Mushtaq

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Young Ho Jeon

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jin Woo Choi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jung Min Han

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Ho Woong Kang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jae Eun Joo

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Youn Hur

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Wonyoung Kang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Heekyoung Yang

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Do-Hyun Nam

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Mi-Sook Lee

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jung Weon Lee

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Eun-Sook Kim

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Kibom Kim

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Doyeun Kim

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Eun Joo Kang

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Youngji Moon

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Kyung Hee Rhee

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Jee Sun Yang

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Gyoonhee Han

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Won Suk Yang

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Cheolju Lee

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Ming-Wei Wang

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

Sunghoon Kim

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

publication date

10 November 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

29-34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription

29 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Interaction of two translational components, lysyl-tRNA synthetase and p40/37LRP, in plasma membrane promotes laminin-dependent cell migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Anti-LRP/LR-specific antibody IgG1-iS18 significantly reduces adhesion and invasion of metastatic lung, cervix, colon and prostate cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3–Gαq coupling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Top-down modulations in the visual form pathway revealed with dynamic causal modeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

A global map of human gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Automated data reduction for hydrogen/deuterium exchange experiments, enabled by high-resolution Fourier transform ion cyclotron resonance mass spectrometry.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Multiple functions of the 37/67-kd laminin receptor make it a suitable target for novel cancer gene therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Enhanced digestion efficiency, peptide ionization efficiency, and sequence resolution for protein hydrogen/deuterium exchange monitored by Fourier transform ion cyclotron resonance mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

67-kDa laminin receptor in human bile duct carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Fast reversed-phase liquid chromatography to reduce back exchange and increase throughput in H/D exchange monitored by FT-ICR mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Lysyl-tRNA synthetase is a target for mutant SOD1 toxicity in mitochondria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Invasion of tumorigenic HT1080 cells is impeded by blocking or downregulating the 37-kDa/67-kDa laminin receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

A universal plate format for increased throughput of assays that monitor multiple aminoacyl transfer RNA synthetase activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Tumor metastasis: mechanistic insights and clinical challenges

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Laminin-induced signaling in tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

The CCPN data model for NMR spectroscopy: development of a software pipeline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

UCSF Chimera--a visualization system for exploratory research and analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Structure of human PRL-3, the phosphatase associated with cancer metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Global gene expression analysis of gastric cancer by oligonucleotide microarrays.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

A fragment of human TrpRS as a potent antagonist of ocular angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Human recombinant [C22A] FK506‐binding protein amide hydrogen exchange rates from mass spectrometry match and extend those from NMR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Prognostic significance of the 67-kilodalton laminin receptor expression in human breast carcinomas.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

The 67 kDa laminin receptor increases tumor aggressiveness by remodeling laminin-1.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

A novel missense mutation p.L76P in the GJB2 gene causing nonsyndromic recessive deafness in a Brazilian family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

Is CMS's requirement for age-specific clinical evidence before considering coverage for CT colonography reasonable and necessary?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

Structure-based maximal affinity model predicts small-molecule druggability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

Complication and failure rates in patients treated for chronic periodontitis and restored with single crowns on teeth and/or implants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

PRIMUS: a Windows PC-based system for small-angle scattering data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

Patient with Down syndrome and implant therapy: a case report

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

67-Kilodalton laminin receptor expression correlates with worse prognostic indicators in non-small cell lung carcinomas.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021855

Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice

30 October 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.1381

Incidence and distribution of experimental metastases in mutant mice with defective organ microenvironments (genotypes Sl/Sld and W/Wv)

21 January 2018

1 reference

12 December 2020

High-performance mass spectrometry: Fourier transform ion cyclotron resonance at 14.5 Tesla

1 reference

12 December 2020

Lipid-protein nanodiscs: possible application in high-resolution NMR investigations of membrane proteins and membrane-active peptides

1 reference

12 December 2020

1 reference

12 December 2020

Overexpression of the 67-kD laminin receptor correlates with tumour progression in human colorectal carcinoma

1 reference

12 December 2020

Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.1381

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

24212136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24212136 AND SRC:MED&resulttype=core&format=json