Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats. (Q33611979)

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12 February 2020

title

Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats (English)

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12 February 2020

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ChEBI release 2020-05-28

5

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12 February 2020

author name string

Yu Hasegawa

1

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12 February 2020

Hidenori Suzuki

2

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12 February 2020

Takumi Sozen

3

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12 February 2020

William Rolland

4

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language of work or name

English

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publication date

25 November 2009

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12 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940275 AND SRC:MED&resulttype=core&format=json

12 February 2020

volume

41

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issue

2

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12 February 2020

page(s)

368-374

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Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke

12 February 2020

cites work

1 reference

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Multifaceted roles of sphingosine-1-phosphate: how does this bioactive sphingolipid fit with acute neurological injury?

21 June 2018

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Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis

21 June 2018

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Oral fingolimod (FTY720) for relapsing multiple sclerosis

21 June 2018

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FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors

21 June 2018

1 reference

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FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.

21 June 2018

1 reference

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Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors

21 June 2018

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

21 June 2018

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FTY720: altered lymphocyte traffic results in allograft protection

21 June 2018

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Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex

21 June 2018

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

21 June 2018

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Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain.

21 June 2018

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Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes.

30 October 2018

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Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells.

30 October 2018

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Cathepsin and calpain inhibitor E64d attenuates matrix metalloproteinase-9 activity after focal cerebral ischemia in rats.

30 October 2018

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Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses.

30 October 2018

1 reference

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Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

30 October 2018

1 reference

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Constitutive expression of the S1P1 receptor in adult tissues.

30 October 2018

1 reference

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Neuroprotective effect of postischemic administration of sodium orthovanadate in rats with transient middle cerebral artery occlusion

30 October 2018

1 reference

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FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration

30 October 2018

1 reference

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FTY 720 prevents ischemic reperfusion damage in rat kidneys

30 October 2018

1 reference

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Immunosuppressant FTY720 inhibits thymocyte emigration

30 October 2018

1 reference

12 December 2020

Mechanisms of erythropoietin-induced brain protection in neonatal hypoxia-ischemia rat model

1 reference

12 December 2020

A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation

1 reference

12 December 2020

A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes

1 reference

12 December 2020

Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway

1 reference

12 December 2020

10.1161/STROKEAHA.109.568899

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940275 AND SRC:MED&resulttype=core&format=json

12 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940275 AND SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19940275

1 reference