Cyclotides, a promising molecular scaffold for peptide-based therapeutics (Q33610239)

28 July 2017

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title

Cyclotides, a promising molecular scaffold for peptide-based therapeutics (English)

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28 July 2017

Krishnappa Jagadish

1

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28 July 2017

Julio A Camarero

series ordinal

2

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28 July 2017

publication date

1 January 2010

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28 July 2017

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28 July 2017

volume

94

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28 July 2017

issue

5

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28 July 2017

page(s)

611-616

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Conotoxin venom peptide therapeutics

28 July 2017

cites work

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

14 July 2018

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14 July 2018

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The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.

14 July 2018

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Development of a cell-based fluorescence resonance energy transfer reporter for Bacillus anthracis lethal factor protease

14 July 2018

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Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Discovery, structure and biological activities of the cyclotides

14 July 2018

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The cyclotides: novel macrocyclic peptides as scaffolds in drug design

14 July 2018

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Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins

14 July 2018

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Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

14 July 2018

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An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides

14 July 2018

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High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes

14 July 2018

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SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

14 July 2018

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Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

14 July 2018

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Oxytocic principles of Oldenlandia affinis

14 July 2018

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Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides

14 July 2018

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The anthelmintic activity of the cyclotides: natural variants with enhanced activity

30 October 2018

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Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides.

30 October 2018

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An asparaginyl endopeptidase mediates in vivo protein backbone cyclization.

30 October 2018

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Biosynthesis of a fully functional cyclotide inside living bacterial cells.

30 October 2018

1 reference

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Biosynthesis of the cyclotide Kalata B1 by using protein splicing

30 October 2018

1 reference

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Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

30 October 2018

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Alternative binding proteins get mature: Rivalling antibodies

30 October 2018

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Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure

30 October 2018

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12 December 2020

Inhibition of platelet aggregation by grafting RGD and KGD sequences on the structural scaffold of small disulfide-rich proteins

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12 December 2020

Total synthesis of the macrocyclic cysteine knot microprotein MCoTI-II

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12 December 2020

Chemical Synthesis of a Circular Protein Domain: Evidence for Folding-Assisted Cyclization

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12 December 2020

Identifiers

DOI

10.1002/BIP.21433

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28 July 2017

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28 July 2017

1 reference