Peptide conjugates as tools for the study of biological signal transduction (Q33603029)

28 July 2017

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title

Peptide conjugates as tools for the study of biological signal transduction (English)

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28 July 2017

3

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28 July 2017

Eisele F

1

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28 July 2017

Owen DJ

series ordinal

2

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28 July 2017

language of work or name

English

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publication date

1 February 1999

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Bioorganic & Medicinal Chemistry

28 July 2017

published in

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28 July 2017

volume

7

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28 July 2017

issue

2

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28 July 2017

page(s)

193-224

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Organic Synthesis and Biological Signal Transduction

28 July 2017

cites work

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The G-protein nanomachine

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cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

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Inositol trisphosphate and calcium signalling

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Protein kinase C, calcium and phospholipid degradation

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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Protein kinase C in the transduction of signals toward and within the cell nucleus

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Making sense of chemicals.

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Rhodopsin and phototransduction: a model system for G protein-linked receptors

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7 January 2021

Signal transduction. How receptors turn Ras on.

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The pathway to signal achievement

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Proteins regulating Ras and its relatives

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Three paths to stress relief

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Receptor tyrosine kinases

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Catalytic activities of glycogenin additional to autocatalytic self-glucosylation

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

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Signal transmission between the plasma membrane and nucleus of T lymphocytes

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7 January 2021

Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012

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7 January 2021

Signal-transduction therapy. A novel approach to disease management

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7 January 2021

Protecting Group Strategies in Organic Synthesis

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7 January 2021

Enzymic Protecting Group Techniques

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7 January 2021

Protein lipidation in cell signaling

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7 January 2021

The dynamic role of palmitoylation in signal transduction

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Enzymatic Synthesis of Peptides andRas Lipopeptides Employing Choline Ester as a Solubilizing, Protecting, and Activating Group

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7 January 2021

The tetrabenzylglucosyloxycarbonyl(BGloc)-group-A carbohydrate-derived enzyme-labile urethane protecting group

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7 January 2021

Synthesis of the Palmitoylated and Farnesylated C-Terminal Lipohexapeptide of the Human N-Ras Protein by Employing an Enzymatically Removable Urethane Protecting Group

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7 January 2021

Chemoenzymatic Synthesis of N-RasLipopeptides

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7 January 2021

Doubly-lipid-modified protein sequence motifs exhibit long-lived anchorage to lipid bilayer membranes

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7 January 2021

16 Synthetic prenylated peptides: Studying prenyl protein-specific endoprotease and other aspects of protein prenylation

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7 January 2021

Synthesis of characteristic lipopeptides of the human N-Ras protein and their evaluation as possible inhibitors of protein farnesyl transferase

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7 January 2021

Synthesis of characteristic lipopeptides of lipid modified proteins employing the allyl ester as protecting group

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7 January 2021

Chemoenzymatic Synthesis of Fluorescent N-Ras Lipopeptides and Their Use in Membrane Localization Studies in Vivo

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7 January 2021

Understanding covalent modifications of proteins by lipids: where cell biology and biophysics mingle

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7 January 2021

The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions

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7 January 2021

Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers.

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7 January 2021

Binding of acylated peptides and fatty acids to phospholipid vesicles: pertinence to myristoylated proteins

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7 January 2021

Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src.

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7 January 2021

S-Acylation and plasma membrane targeting of the farnesylated carboxyl-terminal peptide of N-ras in mammalian fibroblasts

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7 January 2021

Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells

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7 January 2021

A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS)

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7 January 2021

Steady-state kinetic mechanism of Ras farnesyl:protein transferase

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7 January 2021

Chemical biology of protein isoprenylation/methylation

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7 January 2021

S-prenylated cysteine analogues inhibit receptor-mediated G protein activation in native human granulocyte and reconstituted bovine retinal rod outer segment membranes

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7 January 2021

Ras membrane targeting is essential for glucose signaling but not for viability in yeast

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7 January 2021

Evidence for a High Affinity, Saturable, Prenylation-dependent p21 Binding Site in Plasma Membranes

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7 January 2021

Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth

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7 January 2021

Selective Inhibition of Ras-dependent Cell Growth by Farnesylthiosalisylic Acid

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7 January 2021

Dislodgment and Accelerated Degradation of Ras

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7 January 2021

Stringent structural requirements for anti-Ras activity of S-prenyl analogues

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7 January 2021

Protein glycosylation. Structural and functional aspects

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7 January 2021

Biological roles of oligosaccharides: all of the theories are correct

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7 January 2021

Selectins: interpreters of cell-specific carbohydrate information during inflammation

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7 January 2021

Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens

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7 January 2021

HYCRON, an Allylic Anchor for High-Efficiency Solid Phase Synthesis of Protected Peptides and Glycopeptides

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7 January 2021

A strategy for a convergent synthesis of N-linked glycopeptides on a solid support

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7 January 2021

Parallel synthesis and screening of a solid phase carbohydrate library

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7 January 2021

A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE)

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7 January 2021

Constrained glycopeptide ligands for MPRs. Limitations of unprotected phosphorylated building blocks

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7 January 2021

Chemoenzymatic synthesis of O-glycopeptides carrying the tumor associated TN-antigen structure

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7 January 2021

Chemoselective Removal of Protecting Groups from O-Glycosyl Amino Acid and Peptide (Methoxyethoxy)ethyl Esters Using Lipases and Papain

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Immobilization of galactosyltransferase and continuous galactosylation of glycoproteins in a reactor

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Immune Responses of Mice and Human Breast Cancer Patients following Immunization with Synthetic Sialyl‐Tn Conjugated to KLH Plus Detox Adjuvant

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7 January 2021

The regulation of transcription by phosphorylation

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7 January 2021

A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope

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7 January 2021

Combined Fmoc-Alloc strategy for a general SPPS of phosphoserine peptides; preparation of phosphorylation-dependent tau antisera.

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7 January 2021

Synthesis of oligophosphoseryl sequences occurring in casein. Identification of beta-elimination during phosphorylation

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7 January 2021

Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

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7 January 2021

Synthetic study of phosphopeptides related to heat shock protein HSP27

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7 January 2021

Chemoenzymatic Synthesis of a Characteristic Phosphopeptide Fragment of the Raf-1 Kinase

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7 January 2021

Selective enzymatic removal of protecting groups: The phenylacetamide as amino protecting group in phosphopeptide synthesis

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

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7 January 2021

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

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Solid phase synthesis of pp60src-related phosphopeptides via 'global' phosphorylation and their use as substrates for enzymatic phosphorylation by casein kinase-2

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The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal

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Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

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A human peptidyl-prolyl isomerase essential for regulation of mitosis

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Evidence for a NIMA-like mitotic pathway in vertebrate cells

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Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

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Protein folding. Prolyl isomerases join the fold

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7 January 2021

Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease.

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7 January 2021

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau

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7 January 2021

Analysis of phosphorylation of tau with antibodies specific for phosphorylation sites

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7 January 2021

O-GlcNAcylation of key nuclear and cytoskeletal proteins: reciprocity with O-phosphorylation and putative roles in protein multimerization

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Enzymatic Synthesis of a Characteristic Phosphorylated and Glycosylated Peptide Fragment of the Large Subunit of Mammalian RNA Polymerase II

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7 January 2021

Chemoenzymatic Synthesis of a Characteristic Phosphorylated and Glycosylated Peptide Fragment of the Large Subunit of Mammalian RNA Polymerase II

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7 January 2021

Protein-priming of DNA replication

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7 January 2021

Terminal protein-primed DNA amplification

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7 January 2021

Solid-phase synthesis of an RNA nucleopeptide fragment from the nucleoprotein of poliovirus

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Solid-phase synthesis of the nucleopeptide fragment H-Asp-Ser[pAAAGTAAGCC]-Glu-OH from the nucleoprotein of Bacillus subtilis phage phi 29.

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Stepwise solid-phase synthesis of nucleopeptide Phac-Ser(p5′CATCAT)-Gly-Asp-OH from adenovirus-2 nucleoprotein

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7 January 2021

Stepwise Solid-Phase Synthesis of the Nucleopeptide Phac-Phe-Val-Ser(p3'ACT)-Gly-OH

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7 January 2021

Studies on the synthesis of nucleotidyl-peptides. II. The preparation of a nucleotidyl-peptide having a 5'-nucleotidyl-(P-O)-serine phosphodiester bond

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7 January 2021

Chemoenzymatic synthesis of nucleopeptides

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7 January 2021

An enzymatic protecting group strategy for the synthesis of nucleopeptides

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7 January 2021

The Phenylacetyl Group—The First Amino Protecting Group That Can Be Removed Enzymatically from Oligonucleotides in Solution and on a Solid Support

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7 January 2021

Transforming the cell surface through proteolysis

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7 January 2021

Synthetic ligands point to cell surface strategies

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7 January 2021

10.1016/S0968-0896(98)00204-1

Identifiers

DOI

1 reference

28 July 2017

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