The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension (Q33538017)

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English	The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 July 2017

The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension (English)

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Europe PubMed Central

PubMed publication ID

27 July 2017

arterial hypertension

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pulmonary hypertension

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based on heuristic

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Béatrice Desvergne

5

object named as

Béatrice Desvergne

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Laura Moreno

2

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author name string

Louise S Harrington

1

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Europe PubMed Central

PubMed publication ID

27 July 2017

Anna Reed

3

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Europe PubMed Central

PubMed publication ID

27 July 2017

Stephen J Wort

4

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Europe PubMed Central

PubMed publication ID

27 July 2017

Christopher Garland

6

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Europe PubMed Central

PubMed publication ID

27 July 2017

Lan Zhao

7

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Europe PubMed Central

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27 July 2017

Jane A Mitchell

8

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27 July 2017

language of work or name

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publication date

4 March 2010

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Europe PubMed Central

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27 July 2017

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Europe PubMed Central

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27 July 2017

5

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Europe PubMed Central

PubMed publication ID

27 July 2017

3

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Europe PubMed Central

PubMed publication ID

27 July 2017

e9526

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Europe PubMed Central

PubMed publication ID

27 July 2017

copyright license

Creative Commons Attribution 4.0 International

4 March 2010

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April 2022 Public Data File from Crossref

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Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the In

1 reference

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21 June 2018

Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831997

21 June 2018

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

1 reference

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21 June 2018

Updated evidence-based treatment algorithm in pulmonary arterial hypertension.

1 reference

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21 June 2018

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction

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Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.

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21 June 2018

Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries.

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21 June 2018

The Role of PPARgamma in pulmonary vascular disease

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Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium.

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Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta

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21 June 2018

Treatment of pulmonary arterial hypertension

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21 June 2018

Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes

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Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

1 reference

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21 June 2018

Multiple signalling options for prostacyclin.

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21 June 2018

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity

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21 June 2018

Role of prostacyclin in the cardiovascular response to thromboxane A2

1 reference

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21 June 2018

Critical roles of PPAR beta/delta in keratinocyte response to inflammation

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21 June 2018

Sildenafil inhibits hypoxia-induced pulmonary hypertension

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21 June 2018

Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.

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21 June 2018

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

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21 June 2018

Guidelines for the diagnosis and treatment of pulmonary hypertension

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831997

31 October 2018

Antiplatelet actions of statins and fibrates are mediated by PPARs

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31 October 2018

Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts

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31 October 2018

Effects of peroxisome proliferator-activated receptor gamma ligands on monocrotaline-induced pulmonary hypertension in rats

1 reference

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31 October 2018

Survival in primary pulmonary hypertension: the impact of epoprostenol therapy.

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31 October 2018

Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831997

31 October 2018

Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation: relevance to pathogenesis of pulmonary hypertension and vascular remodeling

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Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

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Elucidation of the temporal relationship between endothelial-derived NO and EDHF in mesenteric vessels

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PPARβ/δ Agonists Modulate Platelet Function via a Mechanism Involving PPAR Receptors and Specific Association/Repression of PKCα–Brief Report

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https://pubmed.ncbi.nlm.nih.gov/20209098

12 December 2020

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Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20209098

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Induction of Cyclooxygenase-2 in Human Saphenous Vein and Internal Mammary Artery

1 reference

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Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20209098

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0009526

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Europe PubMed Central

PubMed publication ID

27 July 2017

2010PLoSO...5.9526H

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

ResearchGate publication ID

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