Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression. (Q33440643)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

27 January 2020

title

Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression (English)

1 reference

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27 January 2020

1

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27 January 2020

Ana Ortega-Molina

4

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27 January 2020

Manuel Collado

6

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Óscar Fernández-Capetillo

27 January 2020

7

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27 January 2020

Manuel Serrano

8

1 reference

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27 January 2020

Barbara Martinez-Pastor

3

object named as

Barbara Martinez-Pastor

1 reference

27 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

5

Rebeca Soria

1 reference

27 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

2

Matilde Murga

1 reference

27 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

language of work or name

English

0 references

publication date

7 May 2009

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27 January 2020

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27 January 2020

volume

4

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27 January 2020

issue

5

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27 January 2020

page(s)

e5475

1 reference

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Creative Commons Attribution 4.0 International

27 January 2020

copyright license

start time

7 May 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response

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Global chromatin compaction limits the strength of the DNA damage response

21 June 2018

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Atm is a negative regulator of intestinal neoplasia

21 June 2018

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21 June 2018

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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

21 June 2018

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

21 June 2018

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 June 2018

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Ataxia-telangiectasia and related diseases

21 June 2018

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The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

21 June 2018

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ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

21 June 2018

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The role of double-strand break repair — insights from human genetics

21 June 2018

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Tumour biology: senescence in premalignant tumours

21 June 2018

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 June 2018

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 June 2018

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21 June 2018

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21 June 2018

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Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice

21 June 2018

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Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.

21 June 2018

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p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways

21 June 2018

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

21 June 2018

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"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

21 June 2018

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Induction of senescence by oncogenic Ras.

21 June 2018

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

21 June 2018

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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

21 June 2018

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21 June 2018

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Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

21 June 2018

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Atm is dispensable for p53 apoptosis and tumor suppression triggered by cell cycle dysfunction

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

21 June 2018

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Atm-deficient mice: a paradigm of ataxia telangiectasia

21 June 2018

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21 June 2018

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21 June 2018

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Frequent Activation of c- kis as a Transforming Gene in Fibrosarcomas Induced by Methylcholanthrene

21 June 2018

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Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching

21 June 2018

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Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors

21 January 2018

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The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.

21 January 2018

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ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development.

21 January 2018

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Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

21 January 2018

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Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes

21 January 2018

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Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.

21 January 2018

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Tumor suppression by p53 in the absence of Atm.

21 January 2018

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Tumour biology: Policing of oncogene activity by p53

21 January 2018

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Atm deficiency affects both apoptosis and proliferation to augment Myc-induced lymphomagenesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19421407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of ras oncogenes and expression of tumor-specific transplantation antigens in methylcholanthrene-induced murine fibrosarcomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19421407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The differential effects of mutant p53 alleles on advanced murine lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19421407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0005475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

27 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19421407 AND SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

19421407

1 reference