Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators (Q33400428)

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English	Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

G protein-coupled receptor

0 references

Vsevolod Katritch

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

3

object named as

Ruben Abagyan

0 references

author name string

Kimberly A Reynolds

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

16 January 2009

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Journal of Computer - Aided Molecular Design

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

273-288

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Structure of a beta1-adrenergic G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667566

21 June 2018

Crystal structure of the ligand-free G-protein-coupled receptor opsin

1 reference

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A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

1 reference

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21 June 2018

On the applicability of GPCR homology models to computer-aided drug discovery: a comparison between in silico and crystal structures of the beta2-adrenergic receptor.

1 reference

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21 June 2018

Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation

1 reference

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21 June 2018

GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools update

1 reference

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21 June 2018

Molecular modeling of the second extracellular loop of G-protein coupled receptors and its implication on structure-based virtual screening

1 reference

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21 June 2018

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

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21 June 2018

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

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21 June 2018

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

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21 June 2018

Conformational complexity of G-protein-coupled receptors

1 reference

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GPCR structure-based virtual screening approach for CB2 antagonist search

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Ab initio computational modeling of long loops in G-protein coupled receptors

1 reference

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

1 reference

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Ab initio computational modeling of loops in G-protein-coupled receptors: lessons from the crystal structure of rhodopsin

1 reference

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The Blue Obelisk-interoperability in chemical informatics

1 reference

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Molecular mechanism of 7TM receptor activation--a global toggle switch model

1 reference

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Focused library design in GPCR projects on the example of 5-HT(2c) agonists: comparison of structure-based virtual screening with ligand-based search methods

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The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice

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Ligand-selective receptor conformations revisited: the promise and the problem

1 reference

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The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

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Flexible protein–ligand docking by global energy optimization in internal coordinates

1 reference

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21 June 2018

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

1 reference

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21 June 2018

Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor

1 reference

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A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE).

1 reference

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Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.

1 reference

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Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols

1 reference

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Toward the active conformations of rhodopsin and the beta2-adrenergic receptor

1 reference

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1 reference

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Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

1 reference

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Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands

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1 reference

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1 reference

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Modeling and active site refinement for G protein-coupled receptors: application to the beta-2 adrenergic receptor

1 reference

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1 reference

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Use of the X-ray structure of the Beta2-adrenergic receptor for drug discovery

1 reference

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10.1007/S10822-008-9257-9

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Europe PubMed Central

PubMed publication ID

26 July 2017

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journals/jcamd/ReynoldsKA09

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DBLP Dataset 2021-01-02

28 January 2021

PMC publication ID

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Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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