A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation (Q33394515)

26 July 2017

title

A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation (English)

1 reference

26 July 2017

1 reference

4

Poulomi Acharya

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26 July 2017

7

Maria Almira Correia

1 reference

26 July 2017

Yongqiang Wang

1

1 reference

26 July 2017

Mingxiang Liao

2

1 reference

26 July 2017

Nicholas Hoe

3

1 reference

26 July 2017

Changhui Deng

5

1 reference

26 July 2017

Andrew N Krutchinsky

6

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26 July 2017

language of work or name

English

0 references

publication date

18 December 2008

1 reference

Journal of Biological Chemistry

26 July 2017

published in

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26 July 2017

volume

284

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26 July 2017

issue

9

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26 July 2017

page(s)

5671-5684

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describes a project that uses

26 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2645824/fullTextXML

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures

21 June 2018

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21 June 2018

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Covalent binding to apoprotein is a major fate of heme in a variety of reactions in which cytochrome P-450 is destroyed

21 June 2018

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Degradation of rat hepatic cytochrome P-450p

21 June 2018

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Phosphorylation of hepatic phenobarbital-inducible cytochrome P-450.

21 June 2018

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21 June 2018

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Substrate-, hormone-, and cAMP-regulated cytochrome P450 degradation.

21 June 2018

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Degradation of rat liver cytochromes P450 3A after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: characterization of the proteolytic system

21 June 2018

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Cytochrome P-450 and the activation of promutagens in Saccharomyces cerevisiae

21 June 2018

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Ubiquitin-dependent 26S proteasomal pathway: a role in the degradation of native human liver CYP3A4 expressed in Saccharomyces cerevisiae?

21 June 2018

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Endoplasmic reticulum-associated degradation of cytochrome P450 CYP3A4 in Saccharomyces cerevisiae: further characterization of cellular participants and structural determinants

21 January 2018

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Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

21 January 2018

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Proteolytic degradation of heme-modified hepatic cytochromes P450: A role for phosphorylation, ubiquitination, and the 26S proteasome?

21 January 2018

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Phosphorylation of native and heme-modified CYP3A4 by protein kinase C: a mass spectrometric characterization of the phosphorylated peptides

21 January 2018

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Phosphorylation of cytochrome-P-450-dependent monooxygenase components.

21 January 2018

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Adrenocortical cytochrome P-450 responsible for cholesterol side chain cleavage (P-450scc) is phosphorylated by the calcium-activated, phospholipid-sensitive protein kinase (protein kinase C).

21 January 2018

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Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement.

21 January 2018

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Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C.

21 January 2018

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The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

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Identification of the heme-modified peptides from cumene hydroperoxide-inactivated cytochrome P450 3A4.

21 January 2018

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Stable expression of human cytochrome P4502E1 in HepG2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates

21 January 2018

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Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341.

21 January 2018

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The One-electron Autoxidation of Human Cytochrome P450 3A4

21 January 2018

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Posttranslational modification of hepatic cytochrome P-450. Phosphorylation of phenobarbital-inducible P-450 forms PB-4 (IIB1) and PB-5 (IIB2) in isolated rat hepatocytes and in vivo

21 January 2018

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Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase, protein kinase C and cAMP dependent protein kinase

21 January 2018

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12 December 2020

Purification and characterization of two membrane bound serine proteinases from rat liver microsomes active in degradation of cytochrome P450

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Endocytosis and degradation of the yeast uracil permease under adverse conditions

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Substrate-regulated, cAMP-dependent phosphorylation, denaturation, and degradation of glucocorticoid-inducible rat liver cytochrome P450 3A1.

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Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1

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On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction

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The site of cyclic AMP-dependent protein kinase catalyzed phosphorylation of cytochrome P-450 LM2

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12 December 2020

Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture

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12 December 2020

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

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12 December 2020

Irreversible binding of heme to microsomal protein during inactivation of cytochrome P450 by 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine

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12 December 2020

Relationship between phosphorylation and cytochrome P450 destruction

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12 December 2020

Hormone- and substrate-regulated intracellular degradation of cytochrome P450 (2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes

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12 December 2020

Identifiers

DOI

10.1074/JBC.M806104200

1 reference

26 July 2017

1 reference

26 July 2017

1 reference