Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma (Q33387009)

26 July 2017

title

Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma (English)

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multicenter clinical trial

26 July 2017

main subject

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D A Reardon

1

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26 July 2017

G Dresemann

2

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26 July 2017

S Taillibert

3

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26 July 2017

M Campone

4

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26 July 2017

M van den Bent

5

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26 July 2017

P Clement

6

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26 July 2017

E Blomquist

7

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26 July 2017

L Gordower

8

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26 July 2017

H Schultz

9

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26 July 2017

J Raizer

10

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26 July 2017

P Hau

11

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26 July 2017

J Easaw

12

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26 July 2017

M Gil

13

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26 July 2017

J Tonn

14

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26 July 2017

A Gijtenbeek

15

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26 July 2017

U Schlegel

16

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26 July 2017

P Bergstrom

17

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26 July 2017

S Green

18

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26 July 2017

A Weir

19

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26 July 2017

Z Nikolova

20

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26 July 2017

language of work or name

English

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publication date

10 November 2009

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British Journal of Cancer

26 July 2017

published in

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26 July 2017

volume

101

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26 July 2017

issue

12

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26 July 2017

page(s)

1995-2004

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Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma

26 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme

21 June 2018

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

21 June 2018

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Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.

21 June 2018

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PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

21 June 2018

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High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

21 June 2018

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Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

21 June 2018

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Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma

21 June 2018

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Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.

21 June 2018

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Gleevec-mediated inhibition of Rad51 expression and enhancement of tumor cell radiosensitivity

21 June 2018

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STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake

21 June 2018

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Liquid chromatographic-mass spectrometric assay for quantitation of imatinib and its main metabolite (CGP 74588) in plasma

21 June 2018

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

21 June 2018

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Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases

21 June 2018

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Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux

21 June 2018

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Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

21 June 2018

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Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

21 June 2018

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Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials

21 June 2018

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Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

21 June 2018

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TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors

21 June 2018

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Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas

21 January 2018

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Imatinib and hydroxyurea in pretreated progressive glioblastoma multiforme: a patient series

21 January 2018

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21 January 2018

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21 January 2018

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Characterization of an imatinib-sensitive subset of high-grade human glioma cultures

21 January 2018

1 reference

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Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme

21 January 2018

1 reference

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A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.

21 January 2018

1 reference

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Radiation Therapy and Hydroxyurea Followed by the Combination of 6-Thioguanine and BCNU for the Treatment of Primary Malignant Brain Tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6605411

Bevacizumab plus irinotecan in recurrent glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6605411

Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.BJC.6605411

Prevalence of KIT expression in human tumors

21 January 2018

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Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy

21 January 2018

1 reference

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Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors

31 October 2018

1 reference

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Response criteria for phase II studies of supratentorial malignant glioma

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795431

31 October 2018

Identifiers

DOI

10.1038/SJ.BJC.6605411

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Dimensions Publication ID

26 July 2017

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26 July 2017

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