How Genetics Has Helped Piece Together the MAPK Signaling Pathway (Q33364397)

26 July 2017

1 reference

title

How Genetics Has Helped Piece Together the MAPK Signaling Pathway (English)

1 reference

26 July 2017

author name string

Dariel Ashton-Beaucage

series ordinal

1

1 reference

26 July 2017

Marc Therrien

series ordinal

2

1 reference

26 July 2017

language of work or name

English

0 references

publication date

1 January 2017

1 reference

Methods in Molecular Biology

26 July 2017

published in

1 reference

26 July 2017

volume

1487

1 reference

26 July 2017

page(s)

1-21

1 reference

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

26 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

RAS oncogenes: the first 30 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Integrating signals from RTKs to ERK/MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Hyperactive Ras in developmental disorders and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Signaling through RAS-RAF-MEK-ERK: from basics to bedside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Ras oncogenes: split personalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Regulation of RAF protein kinases in ERK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

MAP kinases and the control of nuclear events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The ERK Cascade: Distinct Functions within Various Subcellular Organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

ERK1/2 MAP kinases: structure, function, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Identification of a nucleotide exchange-promoting activity for p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A cytosolic protein catalyzes the release of GDP from p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The Son of sevenless Gene Product: a Putative Activator of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Genetic dissection of a neurodevelopmental pathway: Son of sevenless functions downstream of the sevenless and EGF receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Cloning of bovine GAP and its interaction with oncogenic ras p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The neurofibromatosis type 1 gene encodes a protein related to GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Requirement for c-ras proteins during viral oncogene transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Generation of oncogenic mouse type C viruses: in vitro selection of carcinoma-inducing variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Activated c-raf gene in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Structure and biological activity of human homologs of the raf/mil oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Raf-1 activates MAP kinase-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Purification and properties of extracellular signal-regulated kinase 1, an insulin-stimulated microtubule-associated protein 2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Sprouty, an intracellular inhibitor of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Spatial regulation of EGFR signaling by Sprouty2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Antagonistic feedback loops involving Rau and Sprouty in the Drosophila eye control neuronal and glial differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Malfunctions within the Cbl interactome uncouple receptor tyrosine kinases from destructive transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Evidence for direct interaction between Sprouty and Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Histidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Modulation of signalling by Sprouty: a developing story

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Activation of the MAP kinase pathway by the protein kinase raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A conserved kinase cascade for MAP kinase activation in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mitogen-activated protein kinases: versatile transducers for cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

KSR is a scaffold required for activation of the ERK/MAPK module

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Critical contribution of linker proteins to Raf kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

KSR modulates signal propagation within the MAPK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The protein kinase KSR interacts with 14-3-3 protein and Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

CNK, a RAF-binding multidomain protein required for RAS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The Drosophila Arf GEF Steppke controls MAPK activation in EGFR signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A dimerization-dependent mechanism drives RAF catalytic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

CNK2 couples NGF signal propagation to multiple regulatory cascades driving cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

KSR and CNK: two scaffolds regulating RAS-mediated RAF activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Unlocking the code of 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

PTP-ER, a novel tyrosine phosphatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Inhibition of mitogen-activated protein kinase by a Drosophila dual-specific phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Tay bridge is a negative regulator of EGFR signalling and interacts with Erk and Mkp3 in the Drosophila melanogaster wing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Conserved regulation of MAP kinase expression by PUF RNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Negative regulation of EGFR/MAPK pathway by Pumilio in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Exon Junction Complex Subunits Are Required to Splice Drosophila MAP Kinase, a Large Heterochromatic Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Genetic screening for signal transduction in the era of network biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

HCOP: a searchable database of human orthology predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

An integrative approach to ortholog prediction for disease-focused and other functional studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

The greater RTK/RAS/ERK signalling pathway: how genetics has helped piece together a signalling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

Complementation of byrl in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/978-1-4939-6424-6_1

10.1007/978-1-4939-6424-6_1

21 January 2018

Identifiers

DOI

1 reference

26 July 2017

1 reference