Toxicity and efficacy of sirolimus: relationship to whole-blood concentrations (Q33332540)

25 July 2017

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title

Toxicity and efficacy of sirolimus: relationship to whole-blood concentrations (English)

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25 July 2017

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Meier-Kriesche HU

1

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25 July 2017

Kaplan B

series ordinal

2

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25 July 2017

publication date

1 January 2000

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25 July 2017

published in

Clinical Therapeutics

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25 July 2017

volume

22 Suppl B

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25 July 2017

page(s)

B93-100

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Inhibition of the immune response by rapamycin, a new antifungal antibiotic

25 July 2017

cites work

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Immunosuppressive effects and safety of a sirolimus/cyclosporine combination regimen for renal transplantation

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Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group

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Use of anti-CD25 monoclonal antibody in combination with rapamycin to eliminate cyclosporine treatment during the induction phase of immunosuppression

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7 January 2021

Effects of the pharmacokinetic interaction between orally administered sirolimus and cyclosporine on the synergistic prolongation of heart allograft survival in rats

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7 January 2021

Sirolimus (rapamycin) potentiates cyclosporine in prevention of acute lung rejection

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7 January 2021

Population pharmacokinetics of sirolimus in kidney transplant patients

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Rapamycin: distribution, pharmacokinetics, and therapeutic range investigations.

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7 January 2021

Distribution of sirolimus in rat tissue

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Relative tissue distributions of cyclosporine and sirolimus after concomitant peroral administration to the rat: evidence for pharmacokinetic interactions

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The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent

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Pharmacokinetics of sirolimus in stable renal transplant patients after multiple oral dose administration

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Prolongation of canine pancreatic islet allograft survival with combined rapamycin and cyclosporine therapy at low doses. Rapamycin efficacy is blood level related

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The relationship of blood concentrations of rapamycin and cyclosporine to suppression of allograft rejection in a rabbit heterotopic heart transplant model

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Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506.

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Synergistic effects of cyclosporine and rapamycin in a chronic nephrotoxicity model

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7 January 2021

10.1016/S0149-2918(00)89026-8

Identifiers

DOI

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25 July 2017

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