Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers (Q33283634)

25 July 2017

title

Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers (English)

1 reference

25 July 2017

Phouthone Keohavong

6

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author name string

Yang Liu

1

1 reference

25 July 2017

Weimin Gao

2

1 reference

25 July 2017

Jill M Siegfried

3

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25 July 2017

Joel L Weissfeld

4

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25 July 2017

James D Luketich

5

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25 July 2017

language of work or name

English

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publication date

3 May 2007

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25 July 2017

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25 July 2017

volume

7

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25 July 2017

page(s)

74

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Mutation and polymorphism in the EGFR-TK domain associated with lung cancer.

25 July 2017

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21 June 2018

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Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

21 June 2018

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Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer

21 June 2018

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Role of the Ras-association domain family 1 tumor suppressor gene in human cancers

21 June 2018

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Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

21 June 2018

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21 June 2018

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Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence

21 June 2018

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EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

21 June 2018

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 June 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 June 2018

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The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases

21 June 2018

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Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia

21 June 2018

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Cell signaling: life or death decisions of ras proteins

21 June 2018

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Identification of a novel Ras-regulated proapoptotic pathway

21 June 2018

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The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

21 June 2018

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Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

21 June 2018

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DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation

21 June 2018

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Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis

21 June 2018

1 reference

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Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 June 2018

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Tobacco smoke carcinogens and lung cancer

21 June 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 June 2018

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p53 in growth control and neoplasia

21 June 2018

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21 June 2018

p53: puzzle and paradigm

1 reference

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Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway

21 June 2018

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Regulation of DNA methylation by the Ras signaling pathway

21 June 2018

1 reference

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Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer

21 June 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

Comparison of p53 mutations between adenocarcinoma and squamous cell carcinoma of the lung: unique spectra involving G to A transitions and G to T transversions in both histologic types.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

RASSF1A gene inactivation in non-small cell lung cancer and its clinical implication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer

21 January 2018

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Clinicopathologic significance of the mutations of the epidermal growth factor receptor gene in patients with non-small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1186/1471-2407-7-74

Relationship of Ras association domain family 1 methylation and K-ras mutation in primary non-small cell lung cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Epigenetic down-regulation of death-associated protein kinase in lung cancers.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

p53 mutations and exposure to environmental tobacco smoke in a multicenter study on lung cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Detection of K-ras mutations in lung carcinomas: relationship to prognosis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1877812

Mutational and Epigenetic Evidence for Independent Pathways for Lung Adenocarcinomas Arising in Smokers and Never Smokers

31 October 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

DAP kinase links the control of apoptosis to metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/1471-2407-7-74

K-ras mutations and RASSF1A promoter methylation in colorectal cancer

21 January 2018

1 reference

12 December 2020

Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women

1 reference

12 December 2020

Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer

1 reference

12 December 2020

Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer

1 reference

12 December 2020

Predicting lung cancer by detecting aberrant promoter methylation in sputum

1 reference

12 December 2020

Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung

1 reference

12 December 2020

Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-7-74

1 reference

Dimensions Publication ID

25 July 2017

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1 reference

25 July 2017

1 reference