Towards a ligand targeted enzyme prodrug therapy: single round panning of a beta-lactamase scaffold library on human cancer cells (Q33272567)

25 July 2017

title

Towards a ligand targeted enzyme prodrug therapy: single round panning of a beta-lactamase scaffold library on human cancer cells (English)

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25 July 2017

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Girja S Shukla

1

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25 July 2017

Christopher J Murray

2

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25 July 2017

Melodie Estabrook

3

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25 July 2017

Guang-Ping Shen

4

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25 July 2017

Volker Schellenberger

5

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25 July 2017

David N Krag

6

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25 July 2017

language of work or name

English

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publication date

1 May 2007

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International Journal of Cancer

25 July 2017

published in

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25 July 2017

volume

120

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25 July 2017

issue

10

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25 July 2017

page(s)

2233-2242

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Mechanisms to improve chemotherapy effectiveness

25 July 2017

cites work

1 reference

Ligand-targeted therapeutics in anticancer therapy

21 January 2018

1 reference

Platinum-taxane combinations in metastatic breast cancer: an evolving role in the era of molecularly targeted therapy

21 January 2018

1 reference

Targeted therapy: wave of the future.

21 January 2018

1 reference

Tumour vascular targeting

21 January 2018

1 reference

Monoclonal antibody therapy of haematological malignancies

21 January 2018

1 reference

Therapeutic cancer targeting peptides

21 January 2018

1 reference

Tumor-activated prodrugs--a new approach to cancer therapy

21 January 2018

1 reference

Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates

21 January 2018

1 reference

Enzyme-catalyzed activation of anticancer prodrugs

21 January 2018

1 reference

Enzyme / Abzyme Prodrug Activation Systems: Potential Use in Clinical Oncology

21 January 2018

1 reference

Selective chemotherapeutic strategies using catalytic antibodies: a common pro-moiety for antibody-directed abzyme prodrug therapy

21 January 2018

1 reference

Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.

21 January 2018

1 reference

A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

21 January 2018

1 reference

In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial.

21 January 2018

1 reference

Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patients with glioblastoma multiforme.

21 January 2018

1 reference

Development of a competitive PCR method for in vitro and in vivo quantification of herpes simplex virus thymidine kinase and neomycin resistance-expressing cells used in a clinical trial

21 January 2018

1 reference

Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: clinical follow-up and improved new vectors

21 January 2018

1 reference

Targeted adenoviral vectors

21 January 2018

1 reference

Adenoviral vectors: systemic delivery and tumor targeting

21 January 2018

1 reference

Gene introduction into animal tissues

21 January 2018

1 reference

The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme-prodrug therapies

21 January 2018

1 reference

The kinetics of antibody binding to membrane antigens in solution and at the cell surface

21 January 2018

1 reference

A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.

21 January 2018

1 reference

In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein

21 January 2018

1 reference

Efficient cancer therapy with a nanobody-based conjugate

21 January 2018

1 reference

Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog

21 January 2018

1 reference

Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

1 reference

A helper phage to improve single-chain antibody presentation in phage display

21 January 2018

1 reference

Phage display selection for cell-specific ligands: development of a screening procedure suitable for small tumor specimens

21 January 2018

1 reference

Construction of stabilized proteins by combinatorial consensus mutagenesis

21 January 2018

1 reference

SmeC, an outer membrane multidrug efflux protein of Stenotrophomonas maltophilia

21 January 2018

1 reference

Development of a sensitive and specific enzyme-linked immunosorbent assay for detecting and quantifying CMY-2 and SHV beta-lactamases

21 January 2018

1 reference

Combinatorial pattern discovery in biological sequences: The TEIRESIAS algorithm

21 January 2018

1 reference

RELIC--a bioinformatics server for combinatorial peptide analysis and identification of protein-ligand interaction sites

21 January 2018

1 reference

Identification of a small peptide that inhibits the phosphorylation of ErbB2 and proliferation of ErbB2 overexpressing breast cancer cells

21 January 2018

1 reference

Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.

21 January 2018

1 reference

Cell-free cloning using phi29 DNA polymerase

21 January 2018

1 reference

In situ phage screening. A method for identification of subnanogram tissue components in situ

21 January 2018

1 reference

Purification and properties of the exocellular beta-lactamase of Actinomadura strain R39.

21 January 2018

1 reference

Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter

21 January 2018

1 reference

TEM-1 beta-lactamase as a scaffold for protein recognition and assay

21 January 2018

1 reference

Modifying the specificity and activity of the Enterobacter cloacae P99 beta-lactamase by mutagenesis within an M13 phage vector

21 January 2018

1 reference

Fusions to beta-lactamase as a reporter for gene expression in live mammalian cells

21 January 2018

1 reference

A beta-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy

21 January 2018

1 reference

Human immune response to monoclonal antibody-enzyme conjugates in ADEPT pilot clinical trial

21 January 2018

1 reference

Fluorobodies combine GFP fluorescence with the binding characteristics of antibodies

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.22138

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25 July 2017

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