Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death. (Q33243843)

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21 January 2020

title

Small, nonpeptide p75NTR ligands induce survival signaling and inhibit proNGF-induced death (English)

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21 January 2020

3

Tao Yang

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21 January 2020

author name string

Stephen M Massa

1

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21 January 2020

Youmei Xie

2

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21 January 2020

Anthony W Harrington

4

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21 January 2020

Mi Lyang Kim

5

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21 January 2020

Sung Ok Yoon

6

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21 January 2020

Rosemary Kraemer

7

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21 January 2020

Laura A Moore

8

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21 January 2020

Barbara L Hempstead

9

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21 January 2020

Frank M Longo

10

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21 January 2020

language of work or name

English

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publication date

1 May 2006

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21 January 2020

number of pages

13

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inferred from page(s)

published in

Journal of Neuroscience

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21 January 2020

volume

26

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issue

20

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21 January 2020

page(s)

5288-5300

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Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

21 January 2020

cites work

1 reference

12 December 2020

Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3

1 reference

12 December 2020

Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 2. Prediction of blood-brain barrier penetration

1 reference

12 December 2020

Ceramide signaling downstream of the p75 neurotrophin receptor mediates the effects of nerve growth factor on outgrowth of cultured hippocampal neurons

1 reference

12 December 2020

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

12 December 2020

Nerve growth factor signaling in caveolae-like domains at the plasma membrane

1 reference

12 December 2020

A designed peptidomimetic agonistic ligand of TrkA nerve growth factor receptors.

1 reference

12 December 2020

Nerve growth factor activation of nuclear factor kappaB through its p75 receptor is an anti-apoptotic signal in RN22 schwannoma cells

1 reference

12 December 2020

Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action

1 reference

12 December 2020

Dimerization-dependent block of the proapoptotic effect of p75(NTR)

1 reference

12 December 2020

A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.

1 reference

12 December 2020

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

12 December 2020

Trichodion, a new inhibitor of inflammatory signal transduction pathways from a Trichosporiella species

1 reference

12 December 2020

NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis

1 reference

12 December 2020

NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells.

1 reference

12 December 2020

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

1 reference

12 December 2020

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

12 December 2020

The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway

1 reference

12 December 2020

3-D pharmacophores in drug discovery

1 reference

12 December 2020

A novel p75NTR signaling pathway promotes survival, not death, of immunopurified neocortical subplate neurons

1 reference

12 December 2020

Pharmacophore modeling and three-dimensional database searching for drug design using catalyst

1 reference

12 December 2020

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

1 reference

12 December 2020

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening

1 reference

12 December 2020

Regulation of cell survival by secreted proneurotrophins

1 reference

12 December 2020

Predicting blood-brain barrier penetration of drugs by polar molecular surface area and molecular volume.

1 reference

12 December 2020

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

1 reference

12 December 2020

Erythropoietin mimetics derived from solution phase combinatorial libraries

1 reference

12 December 2020

Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B.

1 reference

12 December 2020

Identification of potent and novel alpha4beta1 antagonists using in silico screening

1 reference

12 December 2020

Alzheimer's therapeutics: neurotrophin small molecule mimetics

1 reference

12 December 2020

ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

1 reference

12 December 2020

History and evolution of the pharmacophore concept in computer-aided drug design

1 reference

12 December 2020

Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells

1 reference

12 December 2020

Neurotrophins and their receptors: a convergence point for many signalling pathways

1 reference

12 December 2020

Trk receptors: roles in neuronal signal transduction

1 reference

12 December 2020

Leukocyte Antigen-Related Protein Tyrosine Phosphatase Receptor: A Small Ectodomain Isoform Functions as a Homophilic Ligand and Promotes Neurite Outgrowth

1 reference

12 December 2020

Modulation of protein-protein interactions with small organic molecules

1 reference

12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1 reference

12 December 2020

Alzheimer's Therapeutics: Neurotrophin Domain Small Molecule Mimetics

1 reference

12 December 2020

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology

1 reference

12 December 2020

Regulation of interleukin receptor-associated kinase (IRAK) phosphorylation and signaling by iota protein kinase C.

1 reference

12 December 2020

Neurotrophins and their receptors: signaling trios in complex biological systems.

1 reference

12 December 2020

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

12 December 2020

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

1 reference

12 December 2020

Structure of nerve growth factor complexed with the shared neurotrophin receptor p75

1 reference

12 December 2020

Pharmacophore modeling and three dimensional database searching for drug design using catalyst: recent advances

1 reference

12 December 2020

p75NTR--live or let die.

1 reference

12 December 2020

p75NTR-mediated signaling promotes the survival of myoblasts and influences muscle strength

1 reference

12 December 2020

The yin and yang of neurotrophin action

1 reference

12 December 2020

Selective small molecule peptidomimetic ligands of TrkC and TrkA receptors afford discrete or complete neurotrophic activities

1 reference

12 December 2020

The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides

1 reference

12 December 2020

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells

1 reference

12 December 2020

Multiple levels for regulation of TrkA in PC12 cells by nerve growth factor.

1 reference

12 December 2020

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

1 reference

12 December 2020

Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

1 reference

12 December 2020

Mesenchymal and neuronal cell expression of the p75 neurotrophin receptor gene occur by different mechanisms

1 reference

12 December 2020

Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture

1 reference

12 December 2020

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

1 reference

12 December 2020

Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4

1 reference

12 December 2020

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

1 reference

12 December 2020

A computer screening approach to immunoglobulin superfamily structures and interactions: discovery of small non-peptidic CD4 inhibitors as novel immunotherapeutics

1 reference

12 December 2020

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism.

1 reference

12 December 2020

A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration

1 reference

12 December 2020

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival.

1 reference

12 December 2020

A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl

1 reference

12 December 2020

A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns].

1 reference

12 December 2020

Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75

1 reference

12 December 2020

Absence of the p75 neurotrophin receptor alters the pattern of sympathosensory sprouting in the trigeminal ganglia of mice overexpressing nerve growth factor

1 reference

12 December 2020

Electromagnetic fields influence NGF activity and levels following sciatic nerve transection

1 reference

12 December 2020

10.1523/JNEUROSCI.3547-05.2006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16707781 AND SRC:MED&resulttype=core&format=json

21 January 2020

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21 January 2020

PubMed publication ID

16707781

1 reference