A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection (Q33237794)

24 July 2017

title

A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection (English)

1 reference

24 July 2017

Michael A Fischbach

2

0 references

Christopher T. Walsh

series ordinal

4

object named as

Christopher T Walsh

1 reference

24 July 2017

Jonathan R Lai

1

1 reference

24 July 2017

David R Liu

series ordinal

3

1 reference

24 July 2017

language of work or name

English

0 references

publication date

27 March 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 July 2017

published in

1 reference

24 July 2017

volume

103

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24 July 2017

issue

14

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24 July 2017

page(s)

5314-5319

1 reference

Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase

24 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Selective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Solution Structure and Backbone Dynamics of the Holo Form of the Frenolicin Acyl Carrier Protein,

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Ubiquitin: not just for proteasomes anymore

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Vancomycin assembly: nature's way.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Genetics and assembly line enzymology of siderophore biosynthesis in bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Quantitative analysis of the relative contributions of donor acyl carrier proteins, acceptor ketosynthases, and linker regions to intermodular transfer of intermediates in hybrid polyketide synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Combinatorial alanine-scanning

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Solution structure of PCP, a prototype for the peptidyl carrier domains of modular peptide synthetases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Membrane association of the Escherichia coli enterobactin synthase proteins EntB/G, EntE, and EntF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Post-translational modification of polyketide and nonribosomal peptide synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Reconstitution and Characterization of the Escherichia coli Enterobactin Synthetase from EntB, EntE, and EntF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Enterobactin Biosynthesis in Escherichia coli: Isochorismate Lyase (EntB) Is a Bifunctional Enzyme That Is Phosphopantetheinylated by EntD and Then Acylated by EntE Using ATP and 2,3-Dihydroxybenzoate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

A new enzyme superfamily - the phosphopantetheinyl transferases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Additivity of mutant effects assessed by binomial mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459352

Cloning and heterologous expression of the epothilone gene cluster.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Biosynthesis of epothilone intermediates with alternate starter units: engineering polyketide-nonribosomal interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Dissection of the EntF condensation domain boundary and active site residues in nonribosomal peptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

A dynamic model for the structure of acyl carrier protein in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Recognition of hybrid peptidyl carrier proteins/acyl carrier proteins in nonribosomal peptide synthetase modules by the 4'-phosphopantetheinyl transferases AcpS and Sfp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Hybrid nonribosomal peptide-polyketide interfaces in epothilone biosynthesis: minimal requirements at N and C termini of EpoB for elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0601038103

Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases

21 January 2018

1 reference

12 December 2020

Harnessing the biosynthetic code: combinations, permutations, and mutations

1 reference

12 December 2020

Dissecting and exploiting intermodular communication in polyketide synthases

1 reference

12 December 2020

Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal peptide synthesis

1 reference

12 December 2020

Aminoacyl-SNACs as small-molecule substrates for the condensation domains of nonribosomal peptide synthetases

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0601038103

1 reference

24 July 2017

0 references

1 reference

24 July 2017

1 reference