Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo. (Q33188262)

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7 November 2019

title

Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo (English)

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7 November 2019

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1

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7 November 2019

Masayuki Mizui

3

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7 November 2019

author name string

Yoshitugu Takabatake

2

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7 November 2019

Yoshitaka Isaka

4

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7 November 2019

Hiroshi Kawashi

5

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7 November 2019

Harald Rupprecht

6

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7 November 2019

Enyu Imai

7

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7 November 2019

Christian Hugo

8

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7 November 2019

language of work or name

English

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publication date

1 September 2003

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The American Journal of Pathology

7 November 2019

published in

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7 November 2019

volume

163

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7 November 2019

issue

3

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7 November 2019

page(s)

1185-1192

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Latency and activation in the control of TGF-beta

7 November 2019

cites work

1 reference

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Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology

14 July 2018

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The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

14 July 2018

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Real-time quantitative RT-PCR after laser-assisted cell picking

14 July 2018

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Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

14 July 2018

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Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo

14 July 2018

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Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia

14 July 2018

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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

14 July 2018

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TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes

14 July 2018

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Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism

14 July 2018

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Transforming growth factor beta in tissue fibrosis

14 July 2018

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The glomerular response to injury: progression or resolution?

14 July 2018

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Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

14 July 2018

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Thrombospondin in human glomerulopathies. A marker of inflammation and early fibrosis

14 July 2018

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Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

14 July 2018

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The commonest glomerulonephritis in the world: IgA nephropathy.

14 July 2018

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Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix

14 July 2018

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

14 July 2018

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Control of transforming growth factor-beta activity: latency vs. activation

14 July 2018

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

14 July 2018

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Electroporation-mediated gene transfer that targets glomeruli

14 July 2018

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Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

31 October 2018

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31 October 2018

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Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

7 January 2021

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Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis

7 January 2021

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The Fibronectin Production Is Increased by Thrombospondin via Activation of TGF-β in Cultured Human Mesangial Cells

7 January 2021

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Thrombospondin 1 precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease in the rat

7 January 2021

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Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo

7 January 2021

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An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

7 January 2021

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TGF-beta1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation

7 January 2021

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Mesangial cell-derived transforming growth factor-beta 1 reduces macrophage adhesiveness with consequent deactivation

7 January 2021

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The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta

7 January 2021

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Transfer of a mutated gene encoding active transforming growth factor-beta 1 suppresses mitogenesis and IL-1 response in the glomerulus

7 January 2021

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Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation 1

7 January 2021

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12 December 2020

The emerging role of transforming growth factor-beta in kidney diseases

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12 December 2020

Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system

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12 December 2020

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12937160 AND SRC:MED&resulttype=core&format=json

7 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12937160 AND SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

12937160

1 reference