Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia (Q33178068)

23 July 2017

title

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia (English)

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acute promyelocytic leukemia

23 July 2017

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Lallemand-Breitenbach V

1

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23 July 2017

Guillemin MC

2

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23 July 2017

Janin A

3

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23 July 2017

Daniel MT

4

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23 July 2017

Degos L

5

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23 July 2017

Kogan SC

6

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23 July 2017

Bishop JM

7

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23 July 2017

de Thé H

8

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23 July 2017

language of work or name

English

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publication date

1 April 1999

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Journal of Experimental Medicine

23 July 2017

published in

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23 July 2017

volume

189

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23 July 2017

issue

7

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23 July 2017

page(s)

1043-1052

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Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

23 July 2017

cites work

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Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Retinoic acid and arsenic: towards oncogene-targeted treatments of acute promyelocytic leukaemia

21 June 2018

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The promyelocytic leukemia protein PML has a pro‐apoptotic activity mediated through its RING domain

21 June 2018

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Phosphorylation of activation functions AF-1 and AF-2 of RARalpha and RARgamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment

21 June 2018

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21 June 2018

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21 June 2018

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A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

21 June 2018

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21 June 2018

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Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line.

21 June 2018

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The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells

21 June 2018

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In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

21 June 2018

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Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway

21 June 2018

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Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML.

21 June 2018

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PML protein expression in hematopoietic and acute promyelocytic leukemia cells

21 June 2018

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21 June 2018

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A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage

21 June 2018

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

21 June 2018

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21 June 2018

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The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion

21 June 2018

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PML, a growth suppressor disrupted in acute promyelocytic leukemia

21 June 2018

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21 June 2018

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Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

21 June 2018

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A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia

21 June 2018

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Acute promyelocytic leukemia

21 June 2018

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12 December 2020

The PML growth-suppressor has an altered expression in human oncogenesis

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12 December 2020

Stimulation of RARα Activation Function AF-1 through Binding to the General Transcription Factor TFIIH and Phosphorylation by CDK7

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12 December 2020

Arsenic and Apoptosis in the Treatment of Acute Promyelocytic Leukemia

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12 December 2020

Identifiers

DOI

10.1084/JEM.189.7.1043

1 reference

23 July 2017

1 reference

23 July 2017

1 reference