Angiogenesis: regulators and clinical applications (Q31923131)

5 July 2017

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title

Angiogenesis: regulators and clinical applications (English)

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5 July 2017

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Liekens S

1

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5 July 2017

De Clercq E

series ordinal

2

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5 July 2017

Neyts J

series ordinal

3

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5 July 2017

language of work or name

English

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publication date

1 February 2001

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5 July 2017

published in

Biochemical Pharmacology

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5 July 2017

volume

61

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5 July 2017

issue

3

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5 July 2017

page(s)

253-270

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Angiogenesis in cancer, vascular, rheumatoid and other disease

5 July 2017

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Regulation of matrix metalloproteinase expression in tumor invasion.

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Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B

7 January 2021

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Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor

7 January 2021

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Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of flt-1

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Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

7 January 2021

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Matrix Metalloproteinase Inhibition as a Novel Anticancer Strategy: A Review with Special Focus on Batimastat and Marimastat

7 January 2021

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Matrix metalloproteinases in tumour invasion and metastasis

7 January 2021

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Proteolysis in human breast and colorectal cancer

7 January 2021

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Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications

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7 January 2021

Molecular angiogenesis

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Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis

7 January 2021

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TGF-beta and the endothelium during immune injury

7 January 2021

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Transforming growth factor‐β1 stimulates macrophage urokinase expression and release of matrix‐bound basic fibroblast growth factor

7 January 2021

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Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

7 January 2021

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Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

7 January 2021

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VEGFs, receptors and angiogenesis

7 January 2021

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

7 January 2021

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Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

7 January 2021

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Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

7 January 2021

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Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

7 January 2021

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Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells

7 January 2021

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Regulation of vascular endothelial growth factor expression in human colon cancer by interleukin-1beta

7 January 2021

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Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia

7 January 2021

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

7 January 2021

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Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

7 January 2021

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Angiogenesis: how a tumor adapts to hypoxia

7 January 2021

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Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia

7 January 2021

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

7 January 2021

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

7 January 2021

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https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Vascular endothelial growth factor is essential for corpus luteum angiogenesis.

7 January 2021

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https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Vascular endothelial growth factor (VEGF) expression in human coronary atherosclerotic lesions: possible pathophysiological significance of VEGF in progression of atherosclerosis

7 January 2021

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

7 January 2021

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Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

7 January 2021

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New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF.

7 January 2021

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Hypoxia and vascular endothelial growth factor selectively up-regulate angiopoietin-2 in bovine microvascular endothelial cells

7 January 2021

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Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration

7 January 2021

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Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons

7 January 2021

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Basic fibroblast growth factor induces expression of VEGF receptor KDR through a protein kinase C and p44/p42 mitogen-activated protein kinase-dependent pathway

7 January 2021

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Role of soluble mediators in angiogenesis

7 January 2021

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Quantitative export of FGF-2 occurs through an alternative, energy-dependent, non-ER/Golgi pathway.

7 January 2021

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Structural and Functional Diversity in the FGf Receptor Multigene Family

7 January 2021

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Interaction of angiogenic basic fibroblast growth factor with endothelial cell heparan sulfate proteoglycans. Biological implications in neovascularization.

7 January 2021

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Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?

7 January 2021

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Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2

7 January 2021

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Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis

7 January 2021

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Angiogenic factors as tumor markers

7 January 2021

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Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients

7 January 2021

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Serum levels of vascular endothelial growth factor and basic fibroblast growth factor in patients with soft-tissue sarcoma

7 January 2021

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The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

7 January 2021

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

7 January 2021

1 reference

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Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis

7 January 2021

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https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

7 January 2021

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

7 January 2021

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Cell adhesion molecules in angiogenesis

7 January 2021

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Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1.

7 January 2021

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A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis

7 January 2021

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Characterization of E-selectin-deficient mice: demonstration of overlapping function of the endothelial selectins.

7 January 2021

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The rationale and future potential of angiogenesis inhibitors in neoplasia

7 January 2021

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Manipulating angiogenesis. From basic science to the bedside.

7 January 2021

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

7 January 2021

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

7 January 2021

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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

7 January 2021

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The K-fgf/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathway

7 January 2021

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

7 January 2021

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Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

7 January 2021

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Tumour suppression by the human von Hippel-Lindau gene product

7 January 2021

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 January 2021

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Matrix metalloproteinases and metastasis

7 January 2021

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Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

7 January 2021

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Assays for angiogenesis: A review

7 January 2021

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Quantitative angiogenesis assays: Progress and problems

7 January 2021

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Angiogenesis: models and modulators.

7 January 2021

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Models for studying angiogenesis in vivo.

7 January 2021

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Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity

7 January 2021

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

7 January 2021

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Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice

7 January 2021

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Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer

7 January 2021

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Preclinical and clinical studies of MMP inhibitors in cancer

7 January 2021

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Tumor angiogenesis--new drugs on the block

7 January 2021

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Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Decreased angiogenesis and arthritic disease in rabbits treated with an alphavbeta3 antagonist.

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

7 January 2021

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Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

7 January 2021

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Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression

7 January 2021

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Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Angiostatin induces and sustains dormancy of human primary tumors in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Angiostatin binds ATP synthase on the surface of human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis.

7 January 2021

1 reference

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Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells

7 January 2021

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

7 January 2021

1 reference

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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Antiangiogenic activity of the cleaved conformation of the serpin antithrombin

7 January 2021

1 reference

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Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

7 January 2021

1 reference

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Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

7 January 2021

1 reference

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Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Thalidomide is an inhibitor of angiogenesis

7 January 2021

1 reference

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Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent

7 January 2021

1 reference

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Antitumor activity of thalidomide in refractory multiple myeloma

7 January 2021

1 reference

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Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

7 January 2021

1 reference

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Inhibition of fibroblast growth factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Inhibition by Pentosan Polysulfate (PPS) of Heparin-Binding Growth Factors Released From Tumor Cells and Blockage by PPS of Tumor Growth in Animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Modulation of fibroblast growth factor-2 receptor binding, signaling, and mitogenic activity by heparin-mimicking polysulfonated compounds

7 January 2021

1 reference

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Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound

7 January 2021

1 reference

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Recent advances in the treatment of prostate cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

An update on the treatment of hemangiomas in children with interferon alfa-2a

7 January 2021

1 reference

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Successful treatment of infantile hemangiomas with interferon-alpha-2b

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Clinical significance of angiogenic factors in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Association of ovarian Malignancy With Expression of Paltelet-Derived Endothelial Cell Growth Factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Prognostic significance of angiogenesis in human pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Expression of platelet-derived endothelial cell growth factor and its mRNA in uterine endometrium during the menstrual cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

7-Deazaxanthine, a novel prototype inhibitor of thymidine phosphorylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Combined effects of angiostatin and ionizing radiation in antitumour therapy

7 January 2021

1 reference

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Tumor targeting with a selective gelatinase inhibitor

7 January 2021

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Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model

7 January 2021

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Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth

7 January 2021

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A cancer therapy resistant to resistance

7 January 2021

1 reference

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Neoangiogenesis: A putative marker of malignancy in non-small-cell-lung-cancer (NSCLC) development

7 January 2021

2 references

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

7 January 2021

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

inferred from DOI database lookup

7 January 2021

based on heuristic

Correlation between expression of vascular endothelial growth factor and tumor vascularity, and patient outcome in human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma

7 January 2021

1 reference

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Matrix metalloproteinases and their inhibitors in tumour growth and invasion

7 January 2021

1 reference

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Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Mechanism of action and in vivo role of platelet-derived growth factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Indispensable Role of Tissue-Type Plasminogen Activator in Growth Factor-Dependent Tube Formation of Human Microvascular Endothelial Cells in Vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Insulin, insulin-like growth factors, and vascular endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Prostaglandins and gangliosides of tumor microenvironment: their role in angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Oestrogen and endothelial cell angiogenic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

The role of hyaluronan in tumour neovascularization (review).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Interaction of fibroblast growth factor-2 (FGF-2) with free gangliosides: biochemical characterization and biological consequences in endothelial cell cultures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Angiopoietin-1 induces sprouting angiogenesis in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Troponin I is present in human cartilage and inhibits angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Actions of TNF and INF-γ on Angiogenesis In Vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Pigment epithelium-derived factor: a potent inhibitor of angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Inhibition of angiogenesis by interleukin 4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

VEGI, a novel cytokine of the tumor necrosis factor family, is an angiogenesis inhibitor that suppresses the growth of colon carcinomas in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Antiangiogenic tumour therapy: will it work?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Controlling the vasculature: angiogenesis, anti-angiogenesis and vascular targeting of gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Small molecule inhibitors of tumor-promoted angiogenesis, including protein tyrosine kinase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

Significance of angiogenesis in cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(00)00529-3

10.1016/S0006-2952(00)00529-3

7 January 2021

Identifiers

DOI

1 reference

5 July 2017

1 reference