CTLA-4 up-regulation plays a role in tolerance mediated by CD45. (Q31793582)

3 July 2017

title

CTLA-4 up-regulation plays a role in tolerance mediated by CD45. (English)

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3 July 2017

S Fecteau

1

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3 July 2017

G P Basadonna

2

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3 July 2017

A Freitas

3

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3 July 2017

C Ariyan

4

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3 July 2017

M H Sayegh

5

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3 July 2017

D M Rothstein

6

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3 July 2017

language of work or name

English

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publication date

1 January 2001

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3 July 2017

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3 July 2017

volume

2

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3 July 2017

issue

1

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3 July 2017

page(s)

58-63

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

3 July 2017

cites work

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

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Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

1 reference

Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

1 reference

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

21 January 2018

1 reference

CTLA-4: a negative regulator of autoimmune disease.

21 January 2018

1 reference

Immunologic self-tolerance maintained by CD25( )CD4( ) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

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CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

21 January 2018

1 reference

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

21 January 2018

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4 T cells

21 January 2018

1 reference

Lifespan of human lymphocyte subsets defined by CD45 isoforms

21 January 2018

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Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase

21 January 2018

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Isoforms of the transmembrane tyrosine phosphatase CD45 differentially affect T cell recognition.

21 January 2018

1 reference

Antibody-mediated targeting of CD45 isoforms: A novel immunotherapeutic strategy

21 January 2018

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Response of naive antigen-specific CD4 T cells in vitro: characteristics and antigen-presenting cell requirements

21 January 2018

1 reference

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25( )CD4( ) regulatory cells that control intestinal inflammation

21 January 2018

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B7/CD28 costimulation is essential for the homeostasis of the CD4 CD25 immunoregulatory T cells that control autoimmune diabetes

21 January 2018

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Interconversion of CD45R subsets of CD4 T cells in vivo

21 January 2018

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The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation

21 January 2018

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CD4 and CD45 regulate qualitatively distinct patterns of calcium mobilization in individual CD4 T cells.

21 January 2018

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Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

21 January 2018

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Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

21 January 2018

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Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

21 January 2018

2 references

21 January 2018

7 January 2021

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

1 reference

7 January 2021

The second domain of the CD45 protein tyrosine phosphatase is critical for interleukin-2 secretion and substrate recruitment of TCR-zeta in vivo

1 reference

7 January 2021

Membrane CD45R isoform exchange on CD4 T cells is rapid, frequent and dynamic in vivo

1 reference

7 January 2021

Distinct isoforms of the CD45 protein-tyrosine phosphatase differentially regulate interleukin 2 secretion and activation signal pathways involving Vav in T cells

1 reference

7 January 2021

Prevention and reversal of renal allograft rejection by antibody against CD45RB

1 reference

7 January 2021

Identifiers

DOI

10.1038/83175

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Dimensions Publication ID

3 July 2017

1029850663

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