HIPK2: a multitalented partner for transcription factors in DNA damage response and development. (Q31122379)

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3 January 2020

review article

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title

HIPK2: a multitalented partner for transcription factors in DNA damage response and development (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17713576 AND SRC:MED&resulttype=core&format=json

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0 references

1

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3 January 2020

Silvia Soddu

series ordinal

4

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author name string

Andrea Prodosmo

series ordinal

2

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3 January 2020

Francesca Siepi

series ordinal

3

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publication date

1 August 2007

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Biochemistry and Cell Biology

3 January 2020

published in

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volume

85

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issue

4

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page(s)

411-418

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Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

3 January 2020

cites work

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p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

21 January 2018

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Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.

21 January 2018

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The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription

21 January 2018

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Phosphorylation by the DHIPK2 protein kinase modulates the corepressor activity of Groucho

21 January 2018

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Homeodomain-interacting protein kinase 2 is the ionizing radiation-activated p53 serine 46 kinase and is regulated by ATM.

21 January 2018

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Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis

21 January 2018

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HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage

21 January 2018

1 reference

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

21 January 2018

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HMGA1 inhibits the function of p53 family members in thyroid cancer cells.

21 January 2018

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Regulation of p53 functions: let's meet at the nuclear bodies.

21 January 2018

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Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability.

21 January 2018

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Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2.

21 January 2018

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C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs

21 January 2018

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Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation

21 January 2018

1 reference

Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.

21 January 2018

1 reference

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

21 January 2018

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Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification

21 January 2018

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Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.

21 January 2018

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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

21 January 2018

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Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals

21 January 2018

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Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

21 January 2018

1 reference

Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

21 January 2018

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Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo

21 January 2018

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Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2

21 January 2018

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Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)

21 January 2018

1 reference

Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation

21 January 2018

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Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death.

21 January 2018

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The protein kinase complement of the human genome

21 January 2018

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Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.

21 January 2018

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

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High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth

21 January 2018

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High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity.

21 January 2018

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High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2.

21 January 2018

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PEST sequences and regulation by proteolysis

21 January 2018

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MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

21 January 2018

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Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.

21 January 2018

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Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation

21 January 2018

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Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation

21 January 2018

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Live or let die: the cell's response to p53

21 January 2018

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Regulation of transcription factor function by phosphorylation.

21 January 2018

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Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

21 January 2018

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Alteration of nucleosome structure as a mechanism of transcriptional regulation

21 January 2018

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Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

21 January 2018

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Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O07-071

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3 January 2020

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