Emerging techniques for the discovery and validation of therapeutic targets for skeletal diseases (Q31120838)

29 June 2017

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title

Emerging techniques for the discovery and validation of therapeutic targets for skeletal diseases (English)

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29 June 2017

Christine H Cho

1

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29 June 2017

Mark E Nuttall

series ordinal

2

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29 June 2017

language of work or name

English

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publication date

1 December 2002

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Expert Opinion on Therapeutic Targets

29 June 2017

published in

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29 June 2017

volume

6

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29 June 2017

issue

6

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29 June 2017

page(s)

679-689

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Cellular platforms for HTS: three case studies

29 June 2017

cites work

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

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Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

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Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis.

21 January 2018

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A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

21 January 2018

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

21 January 2018

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21 January 2018

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The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification

21 January 2018

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The evolving role of information technology in the drug discovery process

21 January 2018

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An NMR approach to structural proteomics

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Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14728222.6.6.679

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29 June 2017

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