Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides. (Q30909790)

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2 November 2019

title

Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides (English)

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2 November 2019

9

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2 November 2019

10

Roger A H Adan

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2 November 2019

author name string

Wouter A J Nijenhuis

1

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2 November 2019

John A W Kruijtzer

2

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2 November 2019

Nienke Wanders

3

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2 November 2019

Dorien H Vrinten

4

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2 November 2019

Keith M Garner

5

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2 November 2019

Wim M M Schaaper

6

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2 November 2019

Rob H Meloen

7

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2 November 2019

Willem Hendrik Gispen

8

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2 November 2019

publication date

1 February 2003

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2 November 2019

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2 November 2019

volume

24

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2 November 2019

issue

2

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2 November 2019

page(s)

271-280

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Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat

2 November 2019

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Analogs of MTII, lactam derivatives of alpha-melanotropin, modified at the N-terminus, and their selectivity at human melanocortin receptors 3, 4, and 5

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Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro

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Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.

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Structure-function studies on the cyclic peptide MT-II, lactam derivative of alpha-melanotropin

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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

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Molecular cloning, expression, and characterization of a fifth melanocortin receptor

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Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid

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The induction of excessive grooming in the rat by intraventricular application of peptides derived from ACTH: Structure-activity studies

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Agouti Protein Inhibits the Production of Eumelanin and Phaeomelanin in the Presence and Absence of α-Melanocyte Stimulating Hormone

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D-Amino acid scan of gamma-melanocyte-stimulating hormone: importance of Trp(8) on human MC3 receptor selectivity

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Discovery of Prototype Peptidomimetic Agonists at the Human Melanocortin Receptors MC1R and MC4R

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Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors

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7 January 2021

Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions

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Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors

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Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis.

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7 January 2021

Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin recep

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7 January 2021

alpha-Melanotropin: the minimal active sequence in the frog skin bioassay

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Agouti protein can act independently of melanocyte-stimulating hormone to inhibit melanogenesis

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7 January 2021

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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7 January 2021

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Common requirements for melanocortin-4 receptor selectivity of structurally unrelated melanocortin agonist and endogenous antagonist, Agouti protein

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Conformation of the core sequence in melanocortin peptides directs selectivity for the melanocortin MC3 and MC4 receptors

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