Engineering extrinsic disorder to control protein activity in living cells (Q30842709)

13 October 2017

Engineering extrinsic disorder to control protein activity in living cells (English)

1 reference

13 October 2017

5

Ilme Schlichting

1 reference

13 October 2017

6

Nikolay V Dokholyan

1 reference

13 October 2017

2

Miroslaw Tarnawski

1 reference

13 October 2017

Onur Dagliyan

1

1 reference

13 October 2017

Pei-Hsuan Chu

series ordinal

3

1 reference

13 October 2017

David Shirvanyants

series ordinal

4

1 reference

13 October 2017

Klaus M Hahn

series ordinal

7

1 reference

13 October 2017

language of work or name

English

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publication date

1 December 2016

1 reference

13 October 2017

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13 October 2017

354

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13 October 2017

6318

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13 October 2017

1441-1444

1 reference

LOVTRAP: an optogenetic system for photoinduced protein dissociation

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Design of protein switches based on an ensemble model of allostery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Optogenetic approaches to cell migration and beyond

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Vav1 as a central regulator of invadopodia assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Rational design of a ligand-controlled protein conformational switch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Optical control of protein activity by fluorescent protein domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Rapid blue-light-mediated induction of protein interactions in living cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Engineered allosteric activation of kinases in living cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Spatiotemporal control of cell signalling using a light-switchable protein interaction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

A genetically encoded photoactivatable Rac controls the motility of living cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Coordination of Rho GTPase activities during cell protrusion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Designing switchable enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Surface sites for engineering allosteric control in proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Ab initio folding of proteins with all-atom discrete molecular dynamics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Estimation of the available free energy in a LOV2-J alpha photoswitch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

N- and C-terminal flanking regions modulate light-induced signal transduction in the LOV2 domain of the blue light sensor phototropin 1 from Avena sativa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Conditional control of protein function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

The interplay between Src and integrins in normal and tumor biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Vav2 is an activator of Cdc42, Rac1, and RhoA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications

21 June 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

A yeast sensor of ligand binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Structural basis of a phototropin light switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

An Improved Cerulean Fluorescent Protein with Enhanced Brightness and Reduced Reversible Photoswitching

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Evolutionary optimization of fluorescent proteins for intracellular FRET

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Bright cyan fluorescent protein variants identified by fluorescence lifetime screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Integration, scaling, space-group assignment and post-refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Features and development of Coot

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Hexicon 2: automated processing of hydrogen-deuterium exchange mass spectrometry data with improved deuteration distribution estimation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

A High-Content Assay for Biosensor Validation and for Examining Stimuli that Affect Biosensor Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Spatiotemporal dynamics of RhoA activity in migrating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

CellGeo: a computational platform for the analysis of shape changes in cells with complex geometries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Open source software for quantification of cell migration, protrusions, and fluorescence intensities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Imaging and photobleach correction of Mero-CBD, sensor of endogenous Cdc42 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Arp2/3 is critical for lamellipodia and response to extracellular matrix cues but is dispensable for chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

STRIDE: a web server for secondary structure assignment from known atomic coordinates of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Pfam: the protein families database

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

MISTIC: Mutual information server to infer coevolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

The I-TASSER Suite: protein structure and function prediction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

ArchDB 2014: structural classification of loops in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Discrete molecular dynamics: an efficient and versatile simulation method for fine protein characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Automated minimization of steric clashes in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Multiscale modeling of nucleosome dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Spatial and temporal regulation of focal adhesion kinase activity in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Analysis of activated GAPs and GEFs in cell lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

21 January 2018

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAH3404

Interpreting the folding kinetics of helical proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5362825

25 November 2018

Identifiers

DOI

10.1126/SCIENCE.AAH3404

1 reference

release_vvxrlyab4vg6vkqzx562oqdtzu

13 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vvxrlyab4vg6vkqzx562oqdtzu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

13 October 2017

PubMed publication ID

27980211

1 reference