Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway (Q30781182)

18 August 2017

Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway (English)

1 reference

18 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Stéphanie Duhamel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Charlotte Girondel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Pierre-Luc Tanguay

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Laure Voisin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Ron Smits

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Paul S Maddox

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

Sylvain Meloche

8

1 reference

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5 June 2020

publication date

6 May 2016

1 reference

18 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

1631-1642

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities

5 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Aurora A kinase (AURKA) in normal and pathological cell division

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Comprehensive molecular characterization of human colon and rectal cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Chromosomal instability and aneuploidy in cancer: from yeast to man

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Cancer chromosomal instability: therapeutic and diagnostic challenges

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Losing balance: the origin and impact of aneuploidy in cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Causes and consequences of aneuploidy in cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

DNA breaks and chromosome pulverization from errors in mitosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Mechanisms of aneuploidy induction by RAS and RAF oncogenes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Aneuploidy drives genomic instability in yeast

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

The Causes and Consequences of Polyploidy in Normal Development and Cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

The Aurora kinase family in cell division and cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Cytokinesis: placing and making the final cut.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Hyperactive Ras in developmental disorders and cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Tetraploidy, aneuploidy and cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

The FBXW7 beta-form is suppressed in human glioma cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Aurora-A - a guardian of poles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

hCDC4 gene mutations in endometrial cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Deregulated cyclin E induces chromosome instability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4934081

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.

20 June 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Requirements for the destruction of human Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Generation of a tightly regulated doxycycline-inducible model for studying mouse intestinal biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/15384101.2016.1183851

Degradation of human Aurora-A protein kinase is mediated by hCdh1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27152455

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27152455

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/15384101.2016.1183851

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27152455 AND SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

27152455

1 reference