Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes (Q30638019)

15 August 2017

Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes (English)

1 reference

15 August 2017

G C Kaiser

1

1 reference

15 August 2017

F Yan

series ordinal

2

1 reference

15 August 2017

D B Polk

series ordinal

3

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 March 1999

1 reference

15 August 2017

1 reference

15 August 2017

116

1 reference

15 August 2017

3

1 reference

15 August 2017

602-609

1 reference

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Limb and skin abnormalities in mice lacking IKKalpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Role of NF-kappaB in immune and inflammatory responses in the gut.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Activation of nuclear factor kappa B inflammatory bowel disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Current concepts of the etiology and pathogenesis of ulcerative colitis and Crohn's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Cellular localization of tumor necrosis factor (TNF)-alpha transcripts in normal bowel and in necrotizing enterocolitis. TNF gene expression by Paneth cells, intestinal eosinophils, and macrophages.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Inhibition of NF-kappa B by sodium salicylate and aspirin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

NF-kappa B: a lesson in family values

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine in the rheumatic disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Sulfasalazine inhibits the binding of TNF alpha to its receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

An experiment to determine the active therapeutic moiety of sulphasalazine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa Balpha

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor alpha gene expression and the response to interferon in chronic hepatitis C.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Intraluminal colonic release of immunoreactive tumour necrosis factor in chronic ulcerative colitis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3606885

Tumor necrosis factor receptor-mediated signaling pathways

25 November 2018

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Tumour-necrosis-factor antibody treatment in Crohn's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Catalysis by a multiprotein IkappaB kinase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Inhibition of tumor necrosis factor-induced p42/p44 mitogen-activated protein kinase activation by sodium salicylate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Cell density-dependent regulation of PLC gamma 1 tyrosine phosphorylation and catalytic activity in an intestinal cell line (IEC-6).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Sulfasalazine. Multiplicity of action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Systemic effects of cytokines released by gene-transduced tumor cells: marked hyperplasia induced in small bowel by gamma-interferon transfectants through host lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Dependence of epithelial growth of the small intestine on T-cell activation during weaning in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Protective effect of epidermal growth factor in an experimental model of colitis in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Controlled trial of 4-ASA in ulcerative colitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Ceramide: a signal for apoptosis or mitogenesis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Kinase suppressor of Ras is ceramide-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

The NF-kappa B and I kappa B proteins: new discoveries and insights

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Effects of steroid treatment on activation of nuclear factor kappaB in patients with inflammatory bowel disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0016-5085(99)70182-4

Distribution studies of salicylazosulfapyridine and its metabolites

7 January 2021

1 reference

12 December 2020

Possible mode of action of 5-aminosalicylic acid

1 reference

12 December 2020

Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions

1 reference

12 December 2020

Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation

1 reference

12 December 2020

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

12 December 2020

10.1016/S0016-5085(99)70182-4

Identifiers

DOI

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

10029619

1 reference