Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells. (Q30565967)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24347643 AND SRC:MED&resulttype=core&format=json

3 March 2020

title

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells (English)

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3 March 2020

4

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3 March 2020

Bernard Lopez

6

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3 March 2020

author name string

Therese Wilhelm

1

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3 March 2020

Indiana Magdalou

2

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3 March 2020

Aurélia Barascu

3

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3 March 2020

Michelle Debatisse

5

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3 March 2020

language of work or name

English

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publication date

17 December 2013

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Proceedings of the National Academy of Sciences of the United States of America

3 March 2020

published in

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volume

111

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issue

2

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3 March 2020

page(s)

763-768

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How unfinished business from S-phase affects mitosis and beyond

3 March 2020

cites work

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The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

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20 June 2018

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Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

20 June 2018

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

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The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction

20 June 2018

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AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51.

20 June 2018

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Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris

20 June 2018

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A homologous recombination defect affects replication-fork progression in mammalian cells.

20 June 2018

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DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function

20 June 2018

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DNA damage induces Chk1-dependent centrosome amplification.

20 June 2018

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Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function

20 June 2018

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Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells

20 June 2018

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Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication

20 June 2018

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Centrosome aberrations--hen or egg in cancer initiation and progression?

20 June 2018

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

20 June 2018

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

20 June 2018

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Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses

20 June 2018

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Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

20 June 2018

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The good, the bad and the ugly: the practical consequences of centrosome amplification

20 June 2018

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Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

20 June 2018

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Centrosomes split in the presence of impaired DNA integrity during mitosis

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations

20 June 2018

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Rescue of arrested replication forks by homologous recombination

20 June 2018

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Characterization of homologous recombination induced by replication inhibition in mammalian cells

20 June 2018

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Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

20 June 2018

1 reference

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Mechanisms and consequences of replication fork arrest.

20 June 2018

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The importance of repairing stalled replication forks

20 June 2018

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Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

20 June 2018

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Genetically abnormal clones in histologically normal breast tissue

20 June 2018

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Dynamic molecular combing: stretching the whole human genome for high-resolution studies.

20 June 2018

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Loss of heterozygosity in normal tissue adjacent to breast carcinomas.

20 June 2018

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Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

20 June 2018

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Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

20 June 2018

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AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells.

21 January 2018

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DNA damage induce gamma-tubulin-RAD51 nuclear complexes in mammalian cells.

21 January 2018

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Role of RAD51 in sister-chromatid exchanges in mammalian cells.

21 January 2018

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Centrobin regulates the assembly of functional mitotic spindles.

21 January 2018

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Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing

21 January 2018

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DNA mismatch repair and Chk1-dependent centrosome amplification in response to DNA alkylation damage.

21 January 2018

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Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase

21 January 2018

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Ten genes for inherited breast cancer.

21 January 2018

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Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients.

21 January 2018

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Genetic alterations in 'normal' luminal and myoepithelial cells of the breast

26 November 2018

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12 December 2020

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

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12 December 2020

Effects of Hydroxyurea and 1-beta-D-Arabinofuranosyl-cytosine on Deoxyribonucleotide Pools in Mouse Embryo Cells

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CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint

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The Bloom Syndrome Protein Limits the Lethality Associated with RAD51 Deficiency

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Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1311520111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24347643 AND SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24347643 AND SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

24347643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24347643 AND SRC:MED&resulttype=core&format=json