Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling (Q30497945)

12 October 2017

Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling (English)

1 reference

12 October 2017

Anamika M Reed

1

1 reference

12 October 2017

Sohail Z Husain

2

1 reference

12 October 2017

Edwin Thrower

3

1 reference

12 October 2017

Martine Alexandre

4

1 reference

12 October 2017

Ahsan Shah

5

1 reference

12 October 2017

Fred S Gorelick

6

1 reference

12 October 2017

Michael H Nathanson

7

1 reference

12 October 2017

language of work or name

English

0 references

publication date

17 November 2010

1 reference

Journal of Biological Chemistry

12 October 2017

1 reference

12 October 2017

286

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12 October 2017

3

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12 October 2017

1919-1926

1 reference

Astrocytes control breathing through pH-dependent release of ATP

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Acidosis: the prime determinant of depressed sensorium in diabetic ketoacidosis

20 June 2018

1 reference

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Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Clinical practice. Acute pancreatitis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

The ryanodine receptor mediates early zymogen activation in pancreatitis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Ca2 signalling and Ca2 -activated ion channels in exocrine acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Vacuolar ATPase regulates zymogen activation in pancreatic acini

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Effects of increased intracellular cAMP on carbachol-stimulated zymogen activation, secretion, and injury in the pancreatic acinar cell

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites

20 June 2018

1 reference

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Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle

20 June 2018

1 reference

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Modulation of intracellular calcium-release channels by calmodulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Association of diabetic ketoacidosis and acute pancreatitis: observations in 100 consecutive episodes of DKA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Multiple isoforms of the ryanodine receptor are expressed in rat pancreatic acinar cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Polarized expression of Ca2 channels in pancreatic and salivary gland cells. Correlation with initiation and propagation of [Ca2 ]i waves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Changes in intracellular Ca2 concentration produced by the alteration of intracellular pH in rat parotid acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Chloroquine stabilizes pancreatic lysosomes and improves survival of mice with diet-induced acute pancreatitis

20 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

20 June 2018

https://api.crossref.org/works/10.1074/JBC.M110.158329

Evidence that zymogen granules are not a physiologically relevant calcium pool. Defining the distribution of inositol 1,4,5-trisphosphate receptors in pancreatic acinar cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Micromolar and submicromolar Ca2 spikes regulating distinct cellular functions in pancreatic acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Intercellular calcium waves in rat pancreatic acini: mechanism of transmission

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Phosphorylation of serine 2843 in ryanodine receptor-calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Localization of the type 3 inositol 1,4,5-trisphosphate receptor in the Ca2 wave trigger zone of pancreatic acinar cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Effect of pH on binding of agonists and antagonists to rat heart muscarinic receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Effect of pH on muscarinic acetylcholine receptors from rat brainstem

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Characterization of inositol trisphosphate receptor binding in brain. Regulation by pH and calcium.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

The effect of external calcium and pH on inositol trisphosphate-mediated calcium release from cerebellum microsomal fractions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Calcium transport pathways of pancreatic acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Ryanodine receptor of skeletal muscle is a gap junction-type channel.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation by high doses of cholecystokinin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Mechanism of Ca2 wave propagation in pancreatic acinar cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Inactivation of the sarcoplasmic reticulum calcium channel by protein kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023488

Symptomatic lactic acidosis in hospitalized antiretroviral-treated patients with human immunodeficiency virus infection: a report of 12 cases

20 June 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Protons released during pancreatic acinar cell secretion acidify the lumen and contribute to pancreatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Ca2 waves require sequential activation of inositol trisphosphate receptors and ryanodine receptors in pancreatic acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Acinar cell membrane disruption is an early event in experimental acute pancreatitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Solubilization and characterization of CCK receptors from mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Expression and subcellular localization of the ryanodine receptor in rat pancreatic acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Functional role of ryanodine-sensitive Ca2 stores in acidic pH-induced contraction in Wistar Kyoto rat aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Stoichiometric phosphorylation of cardiac ryanodine receptor on serine 2809 by calmodulin-dependent kinase II and protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

Molecular Basis of Calmodulin Binding to Cardiac Muscle Ca2 Release Channel (Ryanodine Receptor)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

pH dependence of inositol 1,4,5-trisphosphate-induced Ca2 release in permeabilized smooth muscle cells of the guinea-pig

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M110.158329

A pH-sensitive, neurogenic pathway mediates disease severity in a model of post-ERCP pancreatitis

21 January 2018

1 reference

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A sudden onset of diabetic ketoacidosis and acute pancreatitis after introduction of mizoribine therapy in a patient with rheumatoid arthritis

21 January 2018

1 reference

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Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

26 November 2018

1 reference

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Menadione-induced apoptosis: roles of cytosolic Ca(2 ) elevations and the mitochondrial permeability transition pore

26 November 2018

1 reference

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Positive and negative effects of nitric oxide on Ca(2 ) sparks: influence of beta-adrenergic stimulation

26 November 2018

1 reference

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Influence of Chloroquine on Diet-Induced Pancreatitis

26 November 2018

1 reference

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Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

26 November 2018

1 reference

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Gap junction communication modulates [Ca2 ]i oscillations and enzyme secretion in pancreatic acini

21 January 2018

1 reference

12 December 2020

Modulation of agonist-activated calcium influx by extracellular pH in rat pancreatic acini

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12 December 2020

Recurrent acute pancreatitis associated with propionic acidemia

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12 December 2020

Local and global cytosolic Ca2 oscillations in exocrine cells evoked by agonists and inositol trisphosphate

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12 December 2020

Modulation of cardiac ryanodine receptors by sorcin

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12 December 2020

Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreas

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12 December 2020

Redox regulation of cardiac and skeletal sarcoplasmic reticulum

1 reference

12 December 2020

Modulation of calcium signals by intracellular pH in isolated rat pancreatic acinar cells

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12 December 2020

Cardiac ischemia oxidizes regulatory thiols on ryanodine receptors: captopril acts as a reducing agent to improve Ca2 uptake by ischemic sarcoplasmic reticulum

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12 December 2020

Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury

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12 December 2020

Intracellular pH-regulatory mechanisms in pancreatic acinar cells. I. Characterization of H and HCO3- transporters

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12 December 2020

Phosphorylation of the porcine skeletal and cardiac muscle sarcoplasmic reticulum ryanodine receptor

1 reference

12 December 2020

Secretagogue-induced changes in intracellular pH and amylase release in mouse pancreatic acini

1 reference

12 December 2020

Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats

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12 December 2020

Superoxide Anion Radical-Triggered Ca2 Release from Cardiac Sarcoplasmic Reticulum through Ryanodine Receptor Ca2 Channel

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.158329

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

21084290

1 reference