Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers (Q30488409)

12 August 2017

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers (English)

1 reference

12 August 2017

0 references

0 references

10

Yvonne Böttcher

1 reference

12 August 2017

Galina Y. Zheleznyakova

Galina Y Zheleznyakova

3

0 references

Sarah Voisin

Sarah Voisin

1

0 references

Matthias Blüher

9

Matthias Blüher

1 reference

12 August 2017

14

Helgi B Schiöth

1 reference

12 August 2017

Markus Sällman Almén

2

1 reference

12 August 2017

Lina Lundberg

4

1 reference

12 August 2017

Sanaz Zarei

5

1 reference

12 August 2017

Sandra Castillo

6

1 reference

12 August 2017

Fia Ence Eriksson

7

1 reference

12 August 2017

Emil K Nilsson

8

1 reference

12 August 2017

Peter Kovacs

11

1 reference

12 August 2017

Janis Klovins

12

1 reference

12 August 2017

Mathias Rask-Andersen

13

1 reference

12 August 2017

8 October 2015

1 reference

12 August 2017

1 reference

12 August 2017

7

1 reference

12 August 2017

103

1 reference

describes a project that uses

12 August 2017

minfi

minfi

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Genetic studies of body mass index yield new insights for obesity biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

New genetic loci link adipose and insulin biology to body fat distribution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Function and information content of DNA methylation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Hormonal regulation of the hypothalamic melanocortin system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genetic and epigenetic regulation of the brain-derived neurotrophic factor in the central nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

A promoter-level mammalian expression atlas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

An atlas of active enhancers across human cell types and tissues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Obesity-associated variants within FTO form long-range functional connections with IRX3

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

DNA methylation and body-mass index: a genome-wide analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

CTCF: an architectural protein bridging genome topology and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

BDNF mediates adaptive brain and body responses to energetic challenges

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

ChAMP: 450k Chip Analysis Methylation Pipeline

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Systematic identification of trans eQTLs as putative drivers of known disease associations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Epigenetic signature of panic disorder: a role of glutamate decarboxylase 1 (GAD1) DNA hypomethylation?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

The Genotype-Tissue Expression (GTEx) project

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Role of BDNF epigenetics in activity-dependent neuronal plasticity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Low-level processing of Illumina Infinium DNA Methylation BeadArrays

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Patterns of methylation heritability in a genome-wide analysis of four brain regions.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Decreased NK cells in patients with head and neck cancer determined in archival DNA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

ChromHMM: automating chromatin-state discovery and characterization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Liver X receptors and fat cell metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Meta-analysis identifies common variants associated with body mass index in east Asians

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Profiling of gender-specific rat plasma proteins associated with susceptibility or resistance to diet-induced obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genome‐Wide Association of BMI in African Americans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Biological, clinical and population relevance of 95 loci for blood lipids

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genome-wide association study of height and body mass index in Australian twin families

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Integrating pathway analysis and genetics of gene expression for genome-wide association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genetic control of individual differences in gene-specific methylation in human brain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

From monogenic to polygenic obesity: recent advances

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Common body mass index-associated variants confer risk of extreme obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated in obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

High-resolution mapping of expression-QTLs yields insight into human gene regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Common variants near MC4R are associated with fat mass, weight and risk of obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Genetics of gene expression and its effect on disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

''R"--project for statistical computing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Analysis of the obesity gene FTO in 14,803 type 1 diabetes cases and controls

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

PACSIN3 overexpression increases adipocyte glucose transport through GLUT1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

The SH2B gene is associated with serum leptin and body fat in normal female twins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

Establishing a standard definition for child overweight and obesity worldwide: international survey

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4599317

SH2B1 CpG-SNP is associated with body weight reduction in obese subjects following a dietary restriction program.

20 June 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

MethylAid: visual and interactive quality control of large Illumina 450k datasets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

Epigenetic down regulation of nerve growth factor during alcohol withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

Firing up mitochondrial activities with PTPMT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

Ablation of LGR4 promotes energy expenditure by driving white-to-brown fat switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S13073-015-0225-4

10.1186/S13073-015-0225-4

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

12 August 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13073-015-0225-4

1 reference

12 August 2017

PubMed publication ID

26449484

1 reference