SecA, the motor of the secretion machine, binds diverse partners on one interactive surface (Q30485740)

15 October 2017

SecA, the motor of the secretion machine, binds diverse partners on one interactive surface (English)

1 reference

15 October 2017

Dylan B Cooper

1

1 reference

15 October 2017

Virginia F Smith

2

1 reference

15 October 2017

Jennine M Crane

3

1 reference

15 October 2017

Hilary C Roth

4

1 reference

15 October 2017

Angela A Lilly

5

1 reference

15 October 2017

Linda L Randall

6

1 reference

15 October 2017

language of work or name

English

0 references

publication date

24 June 2008

1 reference

Journal of Molecular Biology

15 October 2017

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15 October 2017

382

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15 October 2017

1

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15 October 2017

74-87

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Ribosome binding of a single copy of the SecY complex: implications for protein translocation

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Structural Basis for Signal-Sequence Recognition by the Translocase Motor SecA as Determined by NMR

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Bacterial protein secretion through the translocase nanomachine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Selective photoaffinity labeling identifies the signal peptide binding domain on SecA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Sites of interaction of a precursor polypeptide on the export chaperone SecB mapped by site-directed spin labeling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Identification of the preprotein binding domain of SecA.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The conformation of a signal peptide bound by Escherichia coli preprotein translocase SecA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

A large conformational change of the translocation ATPase SecA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Nucleotide binding induces changes in the oligomeric state and conformation of Sec A in a lipid environment: a small-angle neutron-scattering study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

SecB modulates the nucleotide-bound state of SecA and stimulates ATPase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The molecular chaperone SecB is released from the carboxy-terminus of SecA during initiation of precursor protein translocation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Chaperone SecB from Escherichia coli Mediates Kinetic Partitioning via a Dynamic Equilibrium with Its Ligands

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

High selectivity with low specificity: how SecB has solved the paradox of chaperone binding

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Phosphatidylglycerol is involved in protein translocation across Escherichia coli inner membranes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

eMovie: a storyboard-based tool for making molecular movies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

In vivo membrane topology of Escherichia coli SecA ATPase reveals extensive periplasmic exposure of multiple functionally important domains clustering on one face of SecA.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The long alpha-helix of SecA is important for the ATPase coupling of translocation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Disorder-order folding transitions underlie catalysis in the helicase motor of SecA

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Asymmetric binding between SecA and SecB two symmetric proteins: implications for function in export.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

The bacterial ATPase SecA functions as a monomer in protein translocation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Organization of the receptor-kinase signaling array that regulates Escherichia coli chemotaxis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633600

A molecular switch in SecA protein couples ATP hydrolysis to protein translocation

26 November 2018

1 reference

12 December 2020

Reconstitution of Purified Bacterial Preprotein Translocase in Liposomes

1 reference

12 December 2020

Mapping of the docking of SecA onto the chaperone SecB by site-directed spin labeling: insight into the mechanism of ligand transfer during protein export

1 reference

12 December 2020

A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA

1 reference

12 December 2020

Complexes between protein export chaperone SecB and SecA. Evidence for separate sites on SecA providing binding energy and regulatory interactions

1 reference

12 December 2020

10.1016/J.JMB.2008.06.049

Identifiers

DOI

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

18602400

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