Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells. (Q30481027)

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English	Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.	scientific article

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8 January 2020

Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells (English)

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8 January 2020

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8 January 2020

Sarah R Needham

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8 January 2020

Christopher Tynan

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8 January 2020

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8 January 2020

Marisa L Martin-Fernandez

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8 January 2020

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Selene K Roberts

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8 January 2020

Martyn D Winn

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8 January 2020

Roger Barraclough

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21 September 2007

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8 January 2020

Biophysical Journal

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8 January 2020

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8 January 2020

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8 January 2020

803-819

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8 January 2020

Unligated epidermal growth factor receptor forms higher order oligomers within microclusters on A431 cells that are sensitive to tyrosine kinase inhibitor binding.

1 reference

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20 June 2018

Targeted antireceptor therapy with monoclonal antibodies leads to the formation of inactivated tetrameric forms of ErbB receptors

1 reference

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20 June 2018

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

1 reference

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20 June 2018

Single-molecule analysis of epidermal growth factor binding on the surface of living cells.

1 reference

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20 June 2018

Multidimensional single-molecule imaging in live cells using total-internal-reflection fluorescence microscopy.

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20 June 2018

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

1 reference

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20 June 2018

On the nature of low- and high-affinity EGF receptors on living cells

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Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis

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20 June 2018

Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis

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20 June 2018

Growth factor receptors, lipid rafts and caveolae: an evolving story

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Polyproline and the "spectroscopic ruler" revisited with single-molecule fluorescence.

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20 June 2018

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity

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Developments in the CCP4 molecular-graphics project

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20 June 2018

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20 June 2018

EGF signalling amplification induced by dynamic clustering of EGFR.

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20 June 2018

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20 June 2018

Single-molecule three-color FRET

1 reference

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20 June 2018

ElNemo: a normal mode web server for protein movement analysis and the generation of templates for molecular replacement

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20 June 2018

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

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20 June 2018

A structure-based model for ligand binding and dimerization of EGF receptors

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The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function

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20 June 2018

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

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20 June 2018

Intermolecular interactions with/within cell membranes and the trinity of membrane potentials: kinetics and imaging

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20 June 2018

The ATP-waiting conformation of rotating F1-ATPase revealed by single-pair fluorescence resonance energy transfer

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20 June 2018

The store-operated calcium entry pathways in human carcinoma A431 cells: functional properties and activation mechanisms

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20 June 2018

EGF receptor ligands

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20 June 2018

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

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20 June 2018

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

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20 June 2018

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

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20 June 2018

Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

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20 June 2018

Structure of the extracellular region of HER3 reveals an interdomain tether

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20 June 2018

Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling

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20 June 2018

Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae

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20 June 2018

Recruitment of the class II phosphoinositide 3-kinase C2beta to the epidermal growth factor receptor: role of Grb2

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20 June 2018

Cell signaling by receptor tyrosine kinases

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20 June 2018

Real-time studies of the interactions between epidermal growth factor and its receptor during endocytic trafficking

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20 June 2018

Single-molecule imaging of EGFR signalling on the surface of living cells

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20 June 2018

The Protein Data Bank

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20 June 2018

Mutagenesis reveals a role for epidermal growth factor receptor extracellular subdomain IV in ligand binding

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20 June 2018

Hypothermic stress leads to activation of Ras-Erk signaling

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Two EGF molecules contribute additively to stabilization of the EGFR dimer

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20 June 2018

Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation

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High affinity epidermal growth factor receptors on the surface of A431 cells have restricted lateral diffusion

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20 June 2018

Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells

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20 June 2018

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12 December 2020

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EGFR in colorectal cancer: more than a simple receptor

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1 reference

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EGF Receptor Activation: Push Comes to Shove

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EGF mediates multiple signals: dependence on the conditions

1 reference

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12 December 2020

based on heuristic

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1 reference

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10.1529/BIOPHYSJ.107.112623

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8 January 2020

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8 January 2020

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8 January 2020

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