In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea (Q30453822)

29 September 2017

In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea (English)

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29 September 2017

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Raphael Kopan

5

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author name string

Zhiyong Liu

1

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29 September 2017

Zhenyi Liu

2

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29 September 2017

Bradley J Walters

3

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29 September 2017

Thomas Owen

4

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29 September 2017

Jian Zuo

6

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29 September 2017

language of work or name

English

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publication date

31 May 2013

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29 September 2017

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29 September 2017

8

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29 September 2017

5

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29 September 2017

e64903

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Creative Commons Attribution 4.0 International

29 September 2017

start time

31 May 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.

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In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation

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Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal

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Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

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Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.

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Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear.

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Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear

14 July 2018

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Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons

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The challenge of hair cell regeneration

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Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

14 July 2018

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

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Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

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Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

14 July 2018

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Fgf20 is required for sensory epithelial specification in the developing cochlea

14 July 2018

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Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development

14 July 2018

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

14 July 2018

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Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2

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Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

14 July 2018

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Regulation of cell fate in the sensory epithelia of the inner ear.

14 July 2018

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Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear

14 July 2018

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The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

14 July 2018

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14 July 2018

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Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation.

14 July 2018

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14 July 2018

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The Notch ligand Jagged1 is required for inner ear sensory development.

14 July 2018

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14 July 2018

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Notch signalling pathway mediates hair cell development in mammalian cochlea

14 July 2018

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14 July 2018

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Notch1 is required for the coordinate segmentation of somites

14 July 2018

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Notch controls proliferation and differentiation of stem cells in a dose-dependent manner

14 July 2018

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Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode

21 January 2018

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Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.

21 January 2018

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Fate of retinoic acid-activated embryonic cell lineages.

21 January 2018

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The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

21 January 2018

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Rbpj regulates development of prosensory cells in the mammalian inner ear

21 January 2018

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Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea.

21 January 2018

1 reference

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A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt signals mediate a fate decision between otic placode and epidermis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0064903

1 reference

29 September 2017

0 references

1 reference

29 September 2017

PubMed publication ID

23741415

1 reference