Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility (Q30448413)

22 August 2017

Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility (English)

1 reference

steroid biosynthetic process

22 August 2017

1 reference

1 reference

Xiaoping Ma

1

1 reference

22 August 2017

Yanlan Dong

series ordinal

2

1 reference

22 August 2017

Martin M Matzuk

series ordinal

3

1 reference

22 August 2017

T Rajendra Kumar

series ordinal

4

1 reference

22 August 2017

language of work or name

English

0 references

publication date

29 November 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

22 August 2017

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22 August 2017

101

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22 August 2017

49

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22 August 2017

17294-17299

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Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Elevated steroidogenesis, defective reproductive organs, and infertility in transgenic male mice overexpressing human chorionic gonadotropin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Pituitary hormones are not required for sexual differentiation of male mice: phenotype of the T/ebp/Nkx2.1 null mutant mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Origin, differentiation and regulation of fetal and adult Leydig cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Perspective: the ovarian follicle--a perspective in 2001.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Targeted disruption of luteinizing hormone/human chorionic gonadotropin receptor gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Origin, proliferation and differentiation of Leydig cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Elevated luteinizing hormone in prepubertal transgenic mice causes hyperandrogenemia, precocious puberty, and substantial ovarian pathology.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Clinical features of primary ovarian failure caused by a point mutation in the follicle-stimulating hormone receptor gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Molecular aspects of the ontogeny of the pituitary-gonadal axis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Leydig cells: endocrine, paracrine, and autocrine regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Differentiation of adult Leydig cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Glycoprotein Hormones: Structure and Function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Production of sexual steroids in rats during pre- and early postnatal life.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Paracrine regulation of testicular function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

The hypogonadal mouse: reproductive functions restored by gene therapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Sertoli-Leydig cell communications.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

A frame-shift mutation in the androgen receptor gene causes complete androgen insensitivity in the testicular-feminized mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Steroidogenesis during postnatal development in the mouse ovary

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Cell-Cell Communication in the Testis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Gonadotrope-specific expression of the human follicle-stimulating hormone beta-subunit gene in pituitaries of transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Hypogonadism Caused by a Single Amino Acid Substitution in the β Subunit of Luteinizing Hormone

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=535369

Fetal development of Leydig cell activity in the mouse is independent of pituitary gonadotroph function

20 June 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Clinical features of primary ovarian failure caused by a point mutation in the follicle-stimulating hormone receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Targeted disruption of the pituitary glycoprotein hormone alpha-subunit produces hypogonadal and hypothyroid mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Changes in Leydig cell gene expression during development in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Androgen receptor function is required in Sertoli cells for the terminal differentiation of haploid spermatids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0404743101

Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15569941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development of luteinizing hormone action in the perinatal rat ovary

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15569941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0404743101

1 reference

22 August 2017

0 references

1 reference

22 August 2017

PubMed publication ID

15569941

1 reference