Plasmin activates epithelial Na channels by cleaving the gamma subunit. (Q30437590)

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25 December 2019

title

Plasmin activates epithelial Na channels by cleaving the gamma subunit (English)

1 reference

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25 December 2019

author

Helbert Rondon-Berrios

3

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25 December 2019

author name string

Christopher J Passero

1

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25 December 2019

Gunhild M Mueller

2

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25 December 2019

Stevan P Tofovic

4

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25 December 2019

Rebecca P Hughey

5

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25 December 2019

Thomas R Kleyman

6

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25 December 2019

language of work or name

English

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publication date

3 November 2008

1 reference

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

283

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25 December 2019

issue

52

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25 December 2019

page(s)

36586-36591

1 reference

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Plasmin in nephrotic urine activates the epithelial sodium channel

25 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

A segment of gamma ENaC mediates elastase activation of Na transport

20 June 2018

1 reference

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Pathogenesis of oedema in nephrotic syndrome: role of epithelial sodium channel

20 June 2018

1 reference

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Role of proteolysis in the activation of epithelial sodium channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Epithelial Na channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

The epithelial Na channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Urokinase (u-PA) is produced by collecting duct principal cells and is post-transcriptionally regulated by SV40 large-T, arginine vasopressin, and epidermal growth factor

20 June 2018

1 reference

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Profiling serine protease substrate specificity with solution phase fluorogenic peptide microarrays

20 June 2018

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Neutrophil elastase activates near-silent epithelial Na channels and increases airway epithelial Na transport.

20 June 2018

1 reference

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Distinct pools of epithelial sodium channels are expressed at the plasma membrane

20 June 2018

1 reference

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Novel aspects and new roles for the serine protease plasmin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Epithelial sodium channels are activated by furin-dependent proteolysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Serine protease activation of near-silent epithelial Na channels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Protease Modulation of the Activity of the Epithelial Sodium Channel Expressed in Xenopus Oocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

An epithelial serine protease activates the amiloride-sensitive sodium channel

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Localization of urokinase-type plasminogen activator messenger RNA in the normal mouse by in situ hybridization

20 June 2018

1 reference

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Renal and metabolic effects of tempol in obese ZSF1 rats--distinct role for superoxide and hydrogen peroxide in diabetic renal injury

20 June 2018

1 reference

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Defective ENaC processing and function in tissue kallikrein-deficient mice.

26 November 2018

1 reference

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Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Regulation of ENaCs by proteases: An increasingly complex story

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Furin cleavage activates the epithelial Na channel by relieving Na self-inhibition

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Increased apical targeting of renal ENaC subunits and decreased expression of 11betaHSD2 in HgCl2-induced nephrotic syndrome in rats

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Maturation of the epithelial Na channel involves proteolytic processing of the alpha- and gamma-subunits

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Arachidonic acid regulates surface expression of epithelial sodium channels.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Characterization of the selectivity filter of the epithelial sodium channel

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Plasma levels and urinary excretion of fibrinolytic and protease inhibitory proteins in nephrotic syndrome

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605981

Sites of urokinase-type plasminogen activator expression and distribution of its receptor in the normal human kidney

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The action of plasmin on synthetic substrates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasminogen and antithrombin III deficiencies in the childhood nephrotic syndrome associated with plasminogenuria and antithrombinuria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M805676200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18981180 AND SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18981180 AND SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

18981180

1 reference