PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms (Q30434858)

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English	PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms	scientific article

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Europe PubMed Central

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16 October 2017

PARP-inhibitor treatment prevents hypertension induced cardiac remodeling by favorable modulation of heat shock proteins, Akt-1/GSK-3β and several PKC isoforms (English)

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Europe PubMed Central

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16 October 2017

arterial hypertension

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10

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11 June 2020

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Laszlo Deres

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11 June 2020

Eva Bartha

2

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11 June 2020

Anita Palfi

3

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11 June 2020

Krisztian Eros

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11 June 2020

Adam Riba

5

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11 June 2020

Janos Lantos

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11 June 2020

Tamas Kalai

7

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11 June 2020

Kalman Hideg

8

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11 June 2020

Balazs Sumegi

9

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11 June 2020

Kalman Toth

11

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11 June 2020

Robert Halmosi

12

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11 June 2020

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11 July 2014

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16 October 2017

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11 June 2020

9

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11 June 2020

7

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11 June 2020

e102148

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11 June 2020

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Creative Commons Attribution 4.0 International

11 July 2014

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4094529/fullTextXML

based on heuristic

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Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts

1 reference

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20 June 2018

Regulation of MKP-1 expression and MAPK activation by PARP-1 in oxidative stress: a new mechanism for the cytoplasmic effect of PARP-1 activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Apoptosis signal-regulating kinase 1/p38 signaling pathway negatively regulates physiological hypertrophy

1 reference

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20 June 2018

Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins

1 reference

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20 June 2018

Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors

1 reference

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20 June 2018

Mitogen-activated protein kinases in heart development and diseases

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20 June 2018

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

1 reference

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20 June 2018

Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia-reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Heat shock pretreatment inhibited the release of Smac/DIABLO from mitochondria and apoptosis induced by hydrogen peroxide in cardiomyocytes and C2C12 myogenic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Heat shock proteins as emerging therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Protein kinase cascades in the regulation of cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

STRESS signaling pathways that modulate cardiac myocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models

1 reference

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20 June 2018

Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Hypertensive heart disease. A complex syndrome or a hypertensive 'cardiomyopathy'?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system

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20 June 2018

Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation

1 reference

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20 June 2018

In vivo phosphorylation of cardiac troponin I by protein kinase Cbeta2 decreases cardiomyocyte calcium responsiveness and contractility in transgenic mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

20 June 2018

Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study

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20 June 2018

Relation of Left Ventricular Mass and Geometry to Morbidity and Mortality in Uncomplicated Essential Hypertension

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20 June 2018

PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0102148

21 January 2018

PARP inhibition delays transition of hypertensive cardiopathy to heart failure in spontaneously hypertensive rats.

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0102148

21 January 2018

Transmural changes in size, contractile and electrical properties of SHR left ventricular myocytes during compensated hypertrophy

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https://api.crossref.org/works/10.1371/JOURNAL.PONE.0102148

21 January 2018

The role of Akt and mitogen-activated protein kinase systems in the protective effect of poly(ADP-ribose) polymerase inhibition in Langendorff perfused and in isoproterenol-damaged rat hearts

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0102148

21 January 2018

A protein kinase Cepsilon-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2.

1 reference

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0102148

21 January 2018

Renin-Angiotensin Inhibition Reverses Advanced Cardiac Remodeling in Aging Spontaneously Hypertensive Rats

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21 January 2018

Differential Induction of Protein Kinase C Isoforms at the Cardiac Hypertrophy Stage and Congestive Heart Failure Stage in Dahl Salt-Sensitive Rats

1 reference

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21 January 2018

Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4094529

26 November 2018

Alterations in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Left ventricular hypertrophy is associated with worse survival independent of ventricular function and number of coronary arteries severely narrowed

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive evaluation of the time course of change in cardiac function in spontaneously hypertensive rats by echocardiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

12 December 2020

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inferred from PubMed ID database lookup

Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against ischemia-reperfusion in the rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

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inferred from PubMed ID database lookup

Smoking accelerates the progression of hypertension-induced myocardial hypertrophy to heart failure in spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

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based on heuristic

inferred from PubMed ID database lookup

Novel molecular targets in the treatment of cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25014216

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based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0102148

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Europe PubMed Central

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11 June 2020

2014PLoSO...9j2148D

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25014216 AND SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

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11 June 2020

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