Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. (Q30419116)

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17 February 2020

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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity (English)

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11 November 2012

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17 February 2020

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17 February 2020

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44

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17 February 2020

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12

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17 February 2020

page(s)

1341-1348

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

17 February 2020

cites work

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Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

20 June 2018

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PSORS2 is due to mutations in CARD14.

20 June 2018

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Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

20 June 2018

1 reference

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SNP-based large-scale identification of allele-specific gene expression in human B cells

20 June 2018

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Psoriasis and other complex trait dermatoses: from Loci to functional pathways

20 June 2018

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Antimicrobial peptides: old molecules with new ideas

20 June 2018

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Innate immunity: ignored for decades, but not forgotten

20 June 2018

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Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

20 June 2018

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The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

20 June 2018

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Pervasive sharing of genetic effects in autoimmune disease

20 June 2018

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Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2

20 June 2018

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Psoriasis in a nationwide cohort study of patients with celiac disease

20 June 2018

1 reference

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Immune signaling by RIG-I-like receptors

20 June 2018

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Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

20 June 2018

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The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans

20 June 2018

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Promise and pitfalls of the Immunochip

20 June 2018

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Bimodal distribution of RNA expression levels in human skeletal muscle tissue

20 June 2018

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NF-κB signaling pathways regulated by CARMA family of scaffold proteins

20 June 2018

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Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals

20 June 2018

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Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.

20 June 2018

1 reference

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

20 June 2018

1 reference

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A map of human genome variation from population-scale sequencing

20 June 2018

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Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation

20 June 2018

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A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

20 June 2018

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Genome-wide association analysis identifies three psoriasis susceptibility loci

20 June 2018

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Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2

20 June 2018

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Association analyses identify six new psoriasis susceptibility loci in the Chinese population

20 June 2018

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Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

20 June 2018

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An immune response network associated with blood lipid levels

20 June 2018

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Integrating common and rare genetic variation in diverse human populations

20 June 2018

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Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

20 June 2018

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Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

20 June 2018

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Assessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models

20 June 2018

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Variance component model to account for sample structure in genome-wide association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Multiple common variants for celiac disease influencing immune gene expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Rere controls retinoic acid signalling and somite bilateral symmetry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Molecular dissection of psoriasis: integrating genetics and biology

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Dermatology in the Darwin anniversary. Part 2: Evolution of the skin-associated immune system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Multiple Loci within the major histocompatibility complex confer risk of psoriasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Ets-1 is a negative regulator of Th17 differentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

PLINK: a tool set for whole-genome association and population-based linkage analyses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

A new multipoint method for genome-wide association studies by imputation of genotypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Identification and characterization of human polyserase-3, a novel protein with tandem serine-protease domains in the same polypeptide chain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Induction of RhoGAP and pathological changes characteristic of Alzheimer's disease by UAHFEMF discharge in rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Kruppel-like factor 4 is a mediator of proinflammatory signaling in macrophages

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates the expression of interferon-gamma stimulated gene 15 in MCF-7 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Assessing the impact of population stratification on genetic association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Connections between psoriasis and Crohn's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Genomic control for association studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

A Janus kinase inhibitor, JAB, is an interferon-gamma-inducible gene and confers resistance to interferons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Variants in MHC, LCE and IL12B have epistatic effects on psoriasis risk in Chinese population

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Psoriasis in Norwegian twins: contribution of genetic and environmental effects.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510312

Psoriasis: from bed to bench and back

26 November 2018

1 reference

12 December 2020

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

1 reference

12 December 2020

Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells

1 reference

12 December 2020

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity

1 reference

12 December 2020

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads

1 reference

12 December 2020

Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21

1 reference

12 December 2020

Beta3GnT2 (B3GNT2), a major polylactosamine synthase: analysis of B3GNT2-deficient mice

1 reference

12 December 2020

New psoriasis susceptibility genes: momentum for skin-barrier disruption.

1 reference

5 October 2024

https://opencitations.net/index/api/v1/references/10.1038/NG.2467

Identifiers

DOI

10.1038/NG.2467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143863 AND SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143863 AND SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

23143863

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143863 AND SRC:MED&resulttype=core&format=json