Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease. (Q30416730)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24581918 AND SRC:MED&resulttype=core&format=json

9 March 2020

title

Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer's disease (English)

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9 March 2020

1 reference

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3

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9 March 2020

author name string

Jie Gao

series ordinal

1

1 reference

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9 March 2020

Bao-Ling Adam

series ordinal

2

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9 March 2020

language of work or name

English

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publication date

14 February 2014

1 reference

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Bioorganic & Medicinal Chemistry Letters

9 March 2020

published in

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9 March 2020

volume

24

1 reference

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9 March 2020

issue

6

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9 March 2020

page(s)

1472-1478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24581918 AND SRC:MED&resulttype=core&format=json

The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats

9 March 2020

cites work

1 reference

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α7 Nicotinic receptor activation reduces β-amyloid-induced apoptosis by inhibiting caspase-independent death through phosphatidylinositol 3-kinase signaling

20 June 2018

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Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease.

20 June 2018

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Neuroprotective therapeutics for Alzheimer's disease: progress and prospects

20 June 2018

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Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans

20 June 2018

1 reference

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Nicotine increases the expression of neurotrophin receptor tyrosine kinase receptor A in basal forebrain cholinergic neurons

20 June 2018

1 reference

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Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection

20 June 2018

1 reference

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A reversible model of the cognitive impairment associated with schizophrenia in monkeys: potential therapeutic effects of two nicotinic acetylcholine receptor agonists.

20 June 2018

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Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence

20 June 2018

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Multifunctional receptor-directed drugs for disorders of the central nervous system

20 June 2018

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Desensitization of nicotinic acetylcholine receptors as a strategy for drug development

20 June 2018

1 reference

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Cigarette smoke, nicotine and cotinine protect against 6-hydroxydopamine-induced toxicity in SH-SY5Y cells

20 June 2018

1 reference

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Multi-target-directed ligands to combat neurodegenerative diseases

20 June 2018

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Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease

20 June 2018

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Schizophrenia and the alpha7 nicotinic acetylcholine receptor

20 June 2018

1 reference

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Nicotine regulates SH-SY5Y neuroblastoma cell proliferation through the release of brain-derived neurotrophic factor

20 June 2018

1 reference

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Cotinine, a neuroactive metabolite of nicotine: potential for treating disorders of impaired cognition.

20 June 2018

1 reference

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CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases

20 June 2018

1 reference

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Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease

20 June 2018

1 reference

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The potential role of cotinine in the cognitive and neuroprotective actions of nicotine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027973

Cognitive effects of nicotine

20 June 2018

1 reference

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Safety of Cotinine in Humans: Physiologic, Subjective, and Cognitive Effects

20 June 2018

1 reference

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Nicotinic receptor binding of [3H]cytisine, [3H]nicotine and [3H]methylcarbamylcholine in rat brain

20 June 2018

1 reference

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Effect of nicotine and cotinine on the production of oxygen free radicals by neutrophils in smokers and non-smokers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027973

Cotinine reduces amyloid-β aggregation and improves memory in Alzheimer's disease mice

20 June 2018

1 reference

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Cotinine-induced convergence of the cholinergic and PI3 kinase-dependent anti-inflammatory pathways in innate immune cells.

26 November 2018

1 reference

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Nitric oxide-mediated effect of nipradilol, an alpha- and beta-adrenergic blocker, on glutamate neurotoxicity in rat cortical cultures.

26 November 2018

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Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation.

26 November 2018

1 reference

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Cotinine binding to nicotinic acetylcholine receptors in bovine chromaffin cell and rat brain membranes

26 November 2018

1 reference

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Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys.

26 November 2018

1 reference

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Nature of nicotine binding to rat brain P2 fraction

26 November 2018

1 reference

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Sites and mechanisms for nicotine's action in the brain

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24581918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2014.02.008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24581918 AND SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24581918 AND SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

24581918

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24581918 AND SRC:MED&resulttype=core&format=json