Preclinical Studies for Cartilage Repair: Recommendations from the International Cartilage Repair Society (Q30409476)

14 November 2017

Preclinical Studies for Cartilage Repair: Recommendations from the International Cartilage Repair Society (English)

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14 November 2017

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14 November 2017

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Mark B Hurtig

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14 November 2017

3

Lisa A Fortier

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14 November 2017

Ernst B Hunziker

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14 November 2017

Jukka S Jurvelin

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14 November 2017

Pierre Mainil-Varlet

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14 November 2017

C Wayne McIlwraith

8

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14 November 2017

Robert L Sah

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14 November 2017

Robert A Whiteside

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14 November 2017

1 April 2011

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14 November 2017

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14 November 2017

137-152

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ICRS Recommendation Document: Patient-Reported Outcome Instruments for Use in Patients with Articular Cartilage Defects.

14 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Magnetic Resonance Imaging of Cartilage Repair: A Review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Surgical management of articular cartilage defects of the knee

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Joint surface defects: clinical course and cellular response in spontaneous and experimental lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The basic science of the subchondral bone

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The use of hyaluronan after arthroscopic surgery of the knee

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The design and use of animal models for translational research in bone tissue engineering and regenerative medicine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Mesenchymal stem cells and cartilage in situ regeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Increased failure rate of autologous chondrocyte implantation after previous treatment with marrow stimulation techniques

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Preclinical animal models in single site cartilage defect testing: a systematic review

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

FDA regulatory pathways for knee cartilage repair products

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Matrix-induced autologous chondrocyte implantation in sheep: objective assessments including confocal arthroscopy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Matrix-encapsulation cell-seeding technique to prevent cell detachment during arthroscopic implantation of matrix-induced autologous chondrocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Articular cartilage: injury pathways and treatment options

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Development of partial thickness articular cartilage injury in an ovine model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Indentation probing of human articular cartilage: Effect on chondrocyte viability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Material properties of articular cartilage in the rabbit tibial plateau

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffold

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Osteogenic protein-1 in knee arthritis and arthroplasty.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Molecular events of chronic pain: from neuron to whole animal in an animal model of osteoarthritis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Cartilage interstitial fluid load support in unconfined compression.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Neonatal rat cartilage has the capacity for tissue regeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Spontaneous repair of full-thickness defects of articular cartilage in a goat model. A preliminary study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Chondrocyte-seeded collagen matrices implanted in a chondral defect in a canine model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The Subchondral Bone Plate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Osteochondral dowel transplantation for repair of focal defects in the knee: an outcome study using an ovine model.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Rabbit articular cartilage defects treated with autologous cultured chondrocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Physical growth and biological maturation of young athletes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

A histological study of human femoral condylar articular cartilage.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Effect of reduced growth rate on the prevalence and severity of osteochondrosis in gilts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Effects of lesion size and location on equine articular cartilage repair

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Biphasic indentation of articular cartilage--II. A numerical algorithm and an experimental study.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Causes of degenerative joint disease (osteoarthrosis) and dyschondroplasia (osteochondrosis) in pigs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Long-term results of superficial defects in articular cartilage: a scanning electron-microscope study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The resurfacing of adult rabbit articular cartilage by multiple perforations through the subchondral bone

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

The structural architecture of adult mammalian articular cartilage evolves by a synchronized process of tissue resorption and neoformation during postnatal development

20 June 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Maturation-dependent durability of spontaneous cartilage repair in rabbit knee joint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Repair of porcine articular cartilage defect with a biphasic osteochondral composite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Subchondral bone trauma causes cartilage matrix degeneration: an immunohistochemical analysis in a canine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Histological and biochemical changes of experimental meniscus tear in the dog knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Intra-articular hyaluronan following autogenous osteochondral grafting of the knee

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Follow-up of osteochondral plug transfers in a goat model: a 6-month study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Marrow stimulation and chondrocyte transplantation using a collagen matrix for cartilage repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Repair of superficial osteochondral defects with an autologous scaffold-free cartilage construct in a caprine model: implantation method and short-term results.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Magnetic resonance imaging characterization of osteochondral defect repair in a goat model at 8 T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Immature porcine knee cartilage lesions show good healing with or without autologous chondrocyte transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Long term results after implantation of tissue engineered cartilage for the treatment of osteochondral lesions in a minipig model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Phenotypic expression of equine articular chondrocytes grown in three-dimensional cultures supplemented with supraphysiologic concentrations of insulin-like growth factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Concentrated bone marrow aspirate improves full-thickness cartilage repair compared with microfracture in the equine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Evaluation of autologous chondrocyte transplantation via a collagen membrane in equine articular defects: results at 12 and 18 months

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Treatment of articular cartilage defects in horses with polymer-based cartilage tissue engineering grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Fibrous tissue of subchondral cystic lesions in horses produce local mediators and neutral metalloproteinases and cause bone resorption in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Expanded phenotypically stable chondrocytes persist in the repair tissue and contribute to cartilage matrix formation and structural integration in a goat model of autologous chondrocyte implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Histomorphometric analysis of adult articular calcified cartilage zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Effects of calcified cartilage on healing of chondral defects treated with microfracture in horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Subchondral bone reaction associated with chondral defect and attempted cartilage repair in goats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

A comparison of epidural buprenorphine plus detomidine with morphine plus detomidine in horses undergoing bilateral stifle arthroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Articular cartilage degeneration following the treatment of focal cartilage defects with ceramic metal implants and compared with microfracture

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Perilesional changes of focal osteochondral defects in an ovine model and their relevance to human osteochondral injuries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Unconfined compression of articular cartilage: nonlinear behavior and comparison with a fibril-reinforced biphasic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Increasing strain and strain rate strengthen transient stiffness but weaken the response to subsequent compression for articular cartilage in unconfined compression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Indentation testing of human cartilage: sensitivity to articular surface degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Boundary lubrication of articular cartilage: role of synovial fluid constituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Effect of synovial fluid on boundary lubrication of articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1947603511401905

Evaluation of small intestinal submucosa grafts for meniscal regeneration in a clinically relevant posterior meniscectomy model in dogs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Chitosan-glycerol phosphate/blood implants improve hyaline cartilage repair in ovine microfracture defects

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Indentation stiffness of repair tissue after autologous chondrocyte transplantation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Repair of articular cartilage defects with osteogenic protein-1 (BMP-7) in dogs.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300779

Injectable mesenchymal stem cell therapy for large cartilage defects--a porcine model

26 November 2018

1 reference

12 December 2020

A comparative study of articular cartilage thickness in the stifle of animal species used in human pre-clinical studies compared to articular cartilage thickness in the human knee

1 reference

12 December 2020

Prospective evaluation of ground reaction forces in dogs undergoing unilateral total hip replacement

1 reference

12 December 2020

Arthroscopic subchondral bone plate microfracture technique augments healing of large chondral defects in the radial carpal bone and medial femoral condyle of horses

1 reference

12 December 2020

Changes in subchondral bone in cartilage resurfacing--an experimental study in sheep using different types of osteochondral grafts

1 reference

12 December 2020

Repair of osteochondral defects with adipose stem cells and a dual growth factor-releasing scaffold in rabbits

1 reference

12 December 2020

Maturation-dependent repair of untreated osteochondral defects in the rabbit knee joint

1 reference

12 December 2020

BMP-7 protects against progression of cartilage degeneration after impact injury

1 reference

12 December 2020

Bone scintigraphy in the canine cruciate deficiency model of osteoarthritis. Comparison of the unstable and contralateral knee

1 reference

12 December 2020

Biomechanical properties of knee articular cartilage

1 reference

12 December 2020

Transplanted chondrocytes inhibit endochondral ossification within cartilage repair tissue

1 reference

12 December 2020

Enhanced Early Tissue Regeneration after Matrix-Assisted Autologous Mesenchymal Stem Cell Transplantation in Full Thickness Chondral Defects in a Minipig Model

1 reference

12 December 2020

Local delivery of autologous platelet in collagen matrix simulated in situ articular cartilage repair

1 reference

12 December 2020

Chondrocyte-fibrin matrix transplants for resurfacing extensive articular cartilage defects

1 reference

12 December 2020

An experimental canine model for subchondral lesions of the knee joint

1 reference

12 December 2020

Changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation

1 reference

12 December 2020

The role of flow-independent viscoelasticity in the biphasic tensile and compressive responses of articular cartilage

1 reference

12 December 2020

Early events in cartilage repair after subchondral bone microfracture

1 reference

12 December 2020

Confined compression of articular cartilage: linearity in ramp and sinusoidal tests and the importance of interdigitation and incomplete confinement

1 reference

12 December 2020

Long-term results of deep defects in articular cartilage. A scanning electron microscope study

1 reference

12 December 2020

Healing of bone-tendon junction in a bone trough: a goat partial patellectomy model

1 reference

12 December 2020

Delamination rates of tissue flaps used in articular cartilage repair

1 reference

12 December 2020

Cell origin and differentiation in the repair of full-thickness defects of articular cartilage

1 reference

12 December 2020

Durability of regenerated articular cartilage produced by free autogenous periosteal grafts in major full-thickness defects in joint surfaces under the influence of continuous passive motion. A follow-up report at one year

1 reference

12 December 2020

[Integration of periosteum covered autogenous bone grafts with and without autologous chondrocytes. An animal experiment using the Göttinger minipig]

1 reference

12 December 2020

A comparison of abrasion burr arthroplasty and subchondral drilling in the treatment of full-thickness cartilage lesions in the rabbit

1 reference

12 December 2020

Subchondral bone overgrowth in the presence of full-thickness cartilage defects in the knee

1 reference

12 December 2020

Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites

1 reference

12 December 2020

Knee immobilization on meniscal healing after suture: an experimental study in sheep

1 reference

12 December 2020

In vivo evaluation of autologous cartilage fragment-loaded scaffolds implanted into equine articular defects and compared with autologous chondrocyte implantation

1 reference

12 December 2020

Quantitative analysis of long-bone growth in the horse

1 reference

12 December 2020

The influence of skeletal maturity on allogenic synovial mesenchymal stem cell-based repair of cartilage in a large animal model

1 reference

12 December 2020

Autologous osteochondral grafting (mosaic arthroplasty) for treatment of subchondral cystic lesions in the equine stifle and fetlock joints

1 reference

12 December 2020

The repair of experimentally produced defects in rabbit articular cartilage by autologous chondrocyte transplantation

1 reference

12 December 2020

Effect of Cultured Autologous Chondrocytes on Repair of Chondral Defects in a Canine Model*

1 reference

12 December 2020

A fibril-network-reinforced biphasic model of cartilage in unconfined compression

1 reference

12 December 2020

Articular cartilage degeneration after frozen meniscus and Achilles tendon allograft transplantation: experimental study in sheep

1 reference

12 December 2020

Functional adaptation of articular cartilage from birth to maturity under the influence of loading: a biomechanical analysis

1 reference

12 December 2020

The chondrogenic potential of free autogenous periosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion. An experimental investigation in the rabbit

1 reference

12 December 2020

Chondrocyte-seeded hydroxyapatite for repair of large articular cartilage defects. A pilot study in the goat

1 reference

12 December 2020

The effect of defect localization on spontaneous repair of osteochondral defects in a Gottingen minipig model: a retrospective analysis of the medial patellar groove versus the medial femoral condyle

1 reference

12 December 2020

Long-term fate and effects of exercise on sternal cartilage autografts used for repair of large osteochondral defects in horses

1 reference

12 December 2020

Transphyseal vessel involvement in repair of metaphyseal retained cartilage

1 reference

12 December 2020

Identifiers

DOI

10.1177/1947603511401905

1 reference

14 November 2017

1 reference

14 November 2017

PubMed publication ID

26069576

1 reference