Oncogenic role of Merlin/NF2 in glioblastoma (Q30398838)

14 November 2017

Oncogenic role of Merlin/NF2 in glioblastoma (English)

1 reference

14 November 2017

1 reference

P A Guerrero

1

1 reference

14 November 2017

W Yin

series ordinal

2

1 reference

14 November 2017

L Camacho

series ordinal

3

1 reference

14 November 2017

D Marchetti

series ordinal

4

1 reference

14 November 2017

language of work or name

English

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publication date

21 July 2014

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14 November 2017

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14 November 2017

34

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14 November 2017

20

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14 November 2017

2621-2630

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Targeting notch signaling pathway in cancer: clinical development advances and challenges

14 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Merlin, the NF2 gene product

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

NIH Image to ImageJ: 25 years of image analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Loss of Tumor Suppressor Merlin in Advanced Breast Cancer Is due to Post-translational Regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Human homolog of Drosophila expanded, hEx, functions as a putative tumor suppressor in human cancer cell lines independently of the Hippo pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Hes1 is required for contact inhibition of cell proliferation in 3T3-L1 preadipocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Notch signaling in glioblastoma: a developmental drug target?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Merlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Merlin is a potent inhibitor of glioma growth

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Contact-dependent inhibition of EGFR signaling by Nf2/Merlin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Shedding light on Merlin's wizardry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

A functional association between merlin and HEI10, a cell cycle regulator.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Cell cycle-dependent nucleocytoplasmic shuttling of the neurofibromatosis 2 tumour suppressor merlin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

G1 cell cycle arrest due to the inhibition of erbB family receptor tyrosine kinases does not require the retinoblastoma protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

20 June 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of merlin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4302072

Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations

26 November 2018

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Interdomain binding mediates tumor growth suppression by the NF2 gene product

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Frequency and distribution of NF2 mutations in schwannomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2014.185

Merlin: hanging tumor suppression on the Rac

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043298

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Central neurofibromatosis with bilateral acoustic neuroma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043298

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.185

1 reference

Dimensions Publication ID

14 November 2017

0 references

1 reference

14 November 2017

PubMed publication ID

25043298

1 reference