Disorder-to-order conformational transitions in protein structure and its relationship to disease. (Q30376073)

21 June 2017

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title

Disorder-to-order conformational transitions in protein structure and its relationship to disease. (English)

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21 June 2017

author name string

Paola Mendoza-Espinosa

1

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21 June 2017

Victor García-González

2

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21 June 2017

Abel Moreno

3

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21 June 2017

Rolando Castillo

4

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21 June 2017

Jaime Mas-Oliva

5

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21 June 2017

language of work or name

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9 April 2009

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Molecular and Cellular Biochemistry

21 June 2017

published in

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21 June 2017

volume

330

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21 June 2017

issue

1-2

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21 June 2017

page(s)

105-120

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A feline model of experimentally induced islet amyloidosis

21 June 2017

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Heparan sulfate proteoglycan induces the production of NO and TNF-alpha by murine microglia

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Fast kinetics and mechanisms in protein folding

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Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes

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Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype

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Mice devoid of PrP are resistant to scrapie

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Functional amyloid formation within mammalian tissue

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GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing.

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Alpha 2-macroglobulin protects some of the protein constituents of dialysis-associated amyloidosis from protease degradation

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Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca(2 ) stabilization

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

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Scrapie prions aggregate to form amyloid-like birefringent rods

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Retroviral nucleocapsid proteins possess potent nucleic acid strand renaturation activity.

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Vascular oxidative stress in Alzheimer disease

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Finnish hereditary amyloidosis is caused by a single nucleotide substitution in the gelsolin gene

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Protein aggregation: folding aggregates, inclusion bodies and amyloid

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Conformational switching and fibrillogenesis in the amyloidogenic fragment of apolipoprotein a-I.

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12 December 2020

Designing transthyretin mutants affecting tetrameric structure: implications in amyloidogenicity

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12 December 2020

Iron, copper, and iron regulatory protein 2 in Alzheimer's disease and related dementias

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12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

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Equine lysozyme: the molecular basis of folding, self-assembly and innate amyloid toxicity.

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Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus

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Amyloids, prions and the inherent infectious nature of misfolded protein aggregates

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Role of Escherichia coli curli operons in directing amyloid fiber formation

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[Oxidative stress, beta-amyloide peptide and Alzheimer's disease].

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12 December 2020

Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity

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12 December 2020

Variant apolipoprotein AI as a major constituent of a human hereditary amyloid

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12 December 2020

Pathologic conformations of prion proteins

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12 December 2020

DNA strand exchange and selective DNA annealing promoted by the human immunodeficiency virus type 1 nucleocapsid protein

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12 December 2020

Amyloid fibril formation propensity is inherent into the hexapeptide tandemly repeating sequence of the central domain of silkmoth chorion proteins of the A-family

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12 December 2020

Kinetics and thermodynamics of amyloid fibril assembly

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12 December 2020

Protein chemistry. In the footsteps of alchemists

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12 December 2020

Formation of amyloid fibrils by peptides derived from the bacterial cold shock protein CspB

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12 December 2020

Molecular mechanism of the blockade of plasma cholesteryl ester transfer protein by its physiological inhibitor apolipoprotein CI

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12 December 2020

Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?

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12 December 2020

Beta-2-microglobulin-associated amyloidosis

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12 December 2020

The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog

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12 December 2020

The cerebral beta-amyloid angiopathies: hereditary and sporadic

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12 December 2020

Amyloid as a natural product

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12 December 2020

Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.

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12 December 2020

Atypical inflammation in the central nervous system in prion disease

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12 December 2020

Heparin accelerates gelsolin amyloidogenesis

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12 December 2020

Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the β-domain

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12 December 2020

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

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12 December 2020

Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans

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12 December 2020

Conformation of bovine myelin basic protein purified with bound lipids

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12 December 2020

Intrinsic disorder is a key characteristic in partners that bind 14-3-3 proteins.

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12 December 2020

Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure

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12 December 2020

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12 December 2020

Intrinsically disordered protein

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12 December 2020

Effects of sulfate ions on Alzheimer beta/A4 peptide assemblies: implications for amyloid fibril-proteoglycan interactions

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12 December 2020

Protein misfolding, evolution and disease

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12 December 2020

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12 December 2020

A mechanism for plus-strand transfer enhancement by the HIV-1 nucleocapsid protein during reverse transcription

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12 December 2020

Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation

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12 December 2020

Stem-loop SL4 of the HIV-1 Ψ RNA packaging signal exhibits weak affinity for the nucleocapsid protein. structural studies and implications for genome recognition

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12 December 2020

Folding proteins in fatal ways

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12 December 2020

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

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12 December 2020

Intrinsic disorder and protein function

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12 December 2020

The protein trinity--linking function and disorder

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12 December 2020

Sequence complexity of disordered protein

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12 December 2020

Mutation in gelsolin gene in Finnish hereditary amyloidosis

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12 December 2020

The ubiquitous nature of RNA chaperone proteins

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12 December 2020

Molecular chaperones and protein quality control

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12 December 2020

Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein.

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12 December 2020

p53, the cellular gatekeeper for growth and division

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12 December 2020

Amyloid accomplices and enforcers

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12 December 2020

Amyloid fibril formation and protein misassembly: a structural quest for insights into amyloid and prion diseases

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12 December 2020

Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan

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12 December 2020

Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation.

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12 December 2020

The LEF-1 high-mobility group domain undergoes a disorder-to-order transition upon formation of a complex with cognate DNA.

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12 December 2020

Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein

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12 December 2020

A backbone-based theory of protein folding

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12 December 2020

An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

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12 December 2020

Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation.

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12 December 2020

HIV-1 nucleocapsid protein as a nucleic acid chaperone: spectroscopic study of its helix-destabilizing properties, structural binding specificity, and annealing activity

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12 December 2020

Amyloidosis due to a mutation of the gelsolin gene in an American family with lattice corneal dystrophy type II

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12 December 2020

The Sequence Attribute Method for Determining Relationships Between Sequence and Protein Disorder

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12 December 2020

Lipid dependant disorder-to-order conformational transitions in apolipoprotein CI derived peptides

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12 December 2020

In search of new structural states of exchangeable apolipoproteins.

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12 December 2020

Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein

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12 December 2020

Beta-adaptin: key molecule for microglial scavenger receptor function under oxidative stress.

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12 December 2020

Isolation and characterization of a platelet-derived macrophage-binding proteoglycan.

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12 December 2020

Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin

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12 December 2020

Cloning and expression of human islet amyloid polypeptide in cultured cells

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12 December 2020

Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families.

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12 December 2020

Reversible aggregation plays a crucial role on the folding landscape of p53 core domain

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12 December 2020

Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

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12 December 2020

Role of glycosaminoglycans in determining the helicity of paired helical filaments

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12 December 2020

Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease

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12 December 2020

Direct observation of Abeta amyloid fibril growth and inhibition

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12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

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12 December 2020

Prion-inducing domain 2-114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments

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12 December 2020

Understanding the sequence determinants of conformational switching using protein design

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12 December 2020

Metalloendoprotease cleavage triggers gelsolin amyloidogenesis

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12 December 2020

Transthyretin Quaternary and Tertiary Structural Changes Facilitate Misassembly into Amyloid

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12 December 2020

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12 December 2020

Protein disorder and the evolution of molecular recognition: theory, predictions and observations

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12 December 2020

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

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12 December 2020

Rational drug design via intrinsically disordered protein

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12 December 2020

The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

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12 December 2020

Amyloids protect the silkmoth oocyte and embryo

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12 December 2020

The genetics of the amyloidoses

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12 December 2020

Perlecan Binds to the β‐Amyloid Proteins (Aβ) of Alzheimer's Disease, Accelerates Aβ Fibril Formation, and Maintains Aβ Fibril Stability

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12 December 2020

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

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12 December 2020

Prion protein amyloidosis

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12 December 2020

The induction of accelerated murine amyloid with human splenic extract. Probable role of amyloid enhancing factor

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12 December 2020

Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins

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12 December 2020

Prion protein transgenes and the neuropathology in prion diseases

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12 December 2020

Amyloid fibrils from the viewpoint of protein folding

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12 December 2020

Amyloid ion channels: a common structural link for protein-misfolding disease

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12 December 2020

Natively unfolded proteins: a point where biology waits for physics

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12 December 2020

Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition

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12 December 2020

Apolipoprotein E alleles as risk factors in Alzheimer's disease

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12 December 2020

Amyloid fibril formation by an SH3 domain

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12 December 2020

Apolipoprotein A1-derived amyloid in human aortic atherosclerotic plaques

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12 December 2020

Three-dimensional structure of the transthyretin-retinol-binding protein complex

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12 December 2020

Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis

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12 December 2020

Proteomics from the clinical perspective: many hopes and much debate

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12 December 2020

The hydrophobin EAS is largely unstructured in solution and functions by forming amyloid-like structures

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12 December 2020

Theoretical approaches to protein aggregation

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12 December 2020

The role of structural disorder in the function of RNA and protein chaperones

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12 December 2020

Detection of type 1 prion protein in variant Creutzfeldt-Jakob disease

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12 December 2020

Disordered RNA chaperone proteins: from functions to disease

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12 December 2020

Mechanism for nucleic acid chaperone activity of HIV-1 nucleocapsid protein revealed by single molecule stretching.

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12 December 2020

Zinc binding to the HIV-1 nucleocapsid protein: a thermodynamic investigation by fluorescence spectroscopy

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12 December 2020

Sickle cell disease: old discoveries, new concepts, and future promise

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12 December 2020

Identification of prion amyloid filaments in scrapie-infected brain

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12 December 2020

The structural biology of protein aggregation diseases: Fundamental questions and some answers

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12 December 2020

Heparan sulfate proteoglycan in diffuse plaques of hippocampus but not of cerebellum in Alzheimer's disease brain

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12 December 2020

Coupled integration of human immunodeficiency virus type 1 cDNA ends by purified integrase in vitro: stimulation by the viral nucleocapsid protein

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12 December 2020

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

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12 December 2020

Characterization and subcellular localization of human Pmel 17/silver, a 110-kDa (pre)melanosomal membrane protein associated with 5,6,-dihydroxyindole-2-carboxylic acid (DHICA) converting activity

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12 December 2020

Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration

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12 December 2020

The heparin/heparan sulfate-binding site on apo-serum amyloid A. Implications for the therapeutic intervention of amyloidosis.

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12 December 2020

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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12 December 2020

The C-terminus of the beta protein is critical in amyloidogenesis

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12 December 2020

Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core

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12 December 2020

Secreted forms of the amyloid-beta precursor protein are ligands for the class A scavenger receptor.

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12 December 2020

Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase

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12 December 2020

iPDA: integrated protein disorder analyzer

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12 December 2020

Heteronuclear NMR studies of the interaction of tRNA3Lys with HIV-1 nucleocapsid protein11Edited by M. F. Summers

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12 December 2020

A broken alpha -helix in folded alpha -Synuclein

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12 December 2020

Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin

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12 December 2020

Functional amyloid--from bacteria to humans.

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12 December 2020

Intrinsic disorder in scaffold proteins: getting more from less

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12 December 2020

How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription

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12 December 2020

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

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12 December 2020

Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin. Cholesterol acyltransferase

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12 December 2020

Crystal structure of monomeric human -2-microglobulin reveals clues to its amyloidogenic properties

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12 December 2020

Dependence on solution conditions of aggregation and amyloid formation by an SH3 domain

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12 December 2020

Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy

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12 December 2020

Molecular biology of prion diseases

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12 December 2020

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

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12 December 2020

Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element

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12 December 2020

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

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12 December 2020

A novel class of secreted hydrophobic proteins is involved in aerial hyphae formation in Streptomyces coelicolor by forming amyloid-like fibrils

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12 December 2020

A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin

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12 December 2020

Characterizing the conformational ensemble of monomeric polyglutamine.

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12 December 2020

Gelsolin–derived familial amyloidosis caused by asparagine or tyrosine substitution for aspartic acid at residue 187

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12 December 2020

Cortical areas abundant in extracellular matrix chondroitin sulphate proteoglycans are less affected by cytoskeletal changes in Alzheimer's disease

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12 December 2020

NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition

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12 December 2020

Fibrils from synthetic amyloid-related peptides enhance development of experimental AA-amyloidosis in mice

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12 December 2020

Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses

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12 December 2020

Prion Diseases and the BSE Crisis

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12 December 2020

Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin

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12 December 2020

The nosology of Creutzfeldt-Jakob disease and conditions related to the accumulation of PrPCJD in the nervous system

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12 December 2020

Surfing the p53 network

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12 December 2020

Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

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12 December 2020

Overexpression of apoC-I in apoE-null mice: severe hypertriglyceridemia due to inhibition of hepatic lipase

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12 December 2020

Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro

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12 December 2020

Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein

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12 December 2020

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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12 December 2020

Forces between hydrophilic surfaces adsorbed with apolipoprotein AII alpha helices.

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12 December 2020

Intrinsically unstructured proteins

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12 December 2020

10.1007/S11010-009-0105-6

Identifiers

DOI

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Dimensions Publication ID

21 June 2017

1043193547

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