Functional aspects of protein flexibility. (Q30375717)

21 June 2017

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title

Functional aspects of protein flexibility. (English)

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21 June 2017

2

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21 June 2017

Kaare Teilum

1

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Birthe B. Kragelund

object named as

Birthe B Kragelund

series ordinal

3

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publication date

24 March 2009

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Cellular and Molecular Life Sciences

21 June 2017

published in

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21 June 2017

volume

66

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21 June 2017

issue

14

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21 June 2017

page(s)

2231-2247

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Structure and enzymatic break-down of proteins

21 June 2017

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Folding and binding cascades: dynamic landscapes and population shifts

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Conformational constraints for amyloid fibrillation: the importance of being unfolded

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Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold

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Finishing the euchromatic sequence of the human genome

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Structural characterization of a proline-driven conformational switch within the Itk SH2 domain

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Contributions to conformational entropy arising from bond vector fluctuations measured from NMR-derived order parameters: application to protein folding

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Visualization of transient encounter complexes in protein-protein association.

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Protein dynamics from NMR.

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Caspase activation: revisiting the induced proximity model

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Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible.

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Global changes in local protein dynamics reduce the entropic cost of carbohydrate binding in the arabinose-binding protein.

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A practical overview of protein disorder prediction methods

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Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid transfer proteins.

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Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography

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Design of DNA-binding peptides based on the leucine zipper motif

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Correlation between sites of limited proteolysis and segmental mobility in thermolysin

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Molecular recognition by induced fit: how fit is the concept?

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Microsecond molecular dynamics simulation shows effect of slow loop dynamics on backbone amide order parameters of proteins

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Conformational entropy in molecular recognition by proteins

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12 December 2020

The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor-like pair of modules of tissue-type plasminogen activator

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Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA

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Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine protease

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An increase in side chain entropy facilitates effector binding: NMR characterization of the side chain methyl group dynamics in Cdc42Hs

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Energetics of the HIV gp120-CD4 binding reaction

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The atomic structure of protein-protein recognition sites

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12 December 2020

Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

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The interface of protein-protein complexes: analysis of contacts and prediction of interactions

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12 December 2020

From Levinthal to pathways to funnels

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12 December 2020

Protein folding funnels: a kinetic approach to the sequence-structure relationship

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12 December 2020

Unraveling principles of lead discovery: from unfrustrated energy landscapes to novel molecular anchors.

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12 December 2020

The surprising complexity of signal sequences

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12 December 2020

Hydrogen exchange identifies native-state motional domains important in protein folding

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Protein stability indicates divergent evolution of PD-(D/E)XK type II restriction endonucleases.

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Water, water everywhere--except where it matters?

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A hierarchy of timescales in protein dynamics is linked to enzyme catalysis

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12 December 2020

Direct detection of transient alpha-helical states in islet amyloid polypeptide

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Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits

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Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

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12 December 2020

Flexibility in monomeric Cu,Zn superoxide dismutase detected by limited proteolysis and molecular dynamics simulation.

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12 December 2020

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate.

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12 December 2020

The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer

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12 December 2020

Coupled folding and binding with alpha-helix-forming molecular recognition elements

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12 December 2020

Protein misfolding, functional amyloid, and human disease

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12 December 2020

Enzyme dynamics during catalysis measured by NMR spectroscopy

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12 December 2020

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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12 December 2020

The effect of water displacement on binding thermodynamics: concanavalin A

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12 December 2020

Complementarity of Structure Ensembles in Protein-Protein Binding

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12 December 2020

Analysis of binding interactions of pepsin inhibitor-3 to mammalian and malarial aspartic proteases

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12 December 2020

The propagation of binding interactions to remote sites in proteins: analysis of the binding of the monoclonal antibody D1.3 to lysozyme

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12 December 2020

An overview of recent developments in the interpretation and prediction of fast internal protein dynamics

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The unfoldomics decade: an update on intrinsically disordered proteins.

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vGNM: a better model for understanding the dynamics of proteins in crystals

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Correlation between phosphorylation of the chemotaxis protein CheY and its activity at the flagellar motor

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12 December 2020

Prolyl isomerase cyclophilin A regulation of Janus-activated kinase 2 and the progression of human breast cancer

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Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

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Molecular and structural characterization of the domain 2 of hepatitis C virus non-structural protein 5A.

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Protein stability parameters measured by hydrogen exchange

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Mapping protein matrix cavities in human cytoglobin through Xe atom binding

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Structural basis for control by phosphorylation

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Two-state allosteric behavior in a single-domain signaling protein

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Intrinsic disorder in scaffold proteins: getting more from less

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Molecular Principles of the Interactions of Disordered Proteins

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12 December 2020

Entropy in protein folding and in protein-protein interactions

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12 December 2020

Conformational changes associated with protein-protein interactions

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12 December 2020

Point mutations and sequence variability in proteins: redistributions of preexisting populations.

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12 December 2020

Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution

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12 December 2020

Energetics of protein folding

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12 December 2020

Application of a Theory of Enzyme Specificity to Protein Synthesis

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Dynamic energy landscape view of coupled binding and protein conformational change: induced-fit versus population-shift mechanisms

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Characterization of the backbone and side chain dynamics of the CaM-CaMKIp complex reveals microscopic contributions to protein conformational entropy

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12 December 2020

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

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N-glycosylation/deglycosylation as a mechanism for the post-translational modification/remodification of proteins

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

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12 December 2020

Increased protein backbone conformational entropy upon hydrophobic ligand binding

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StoneHinge: hinge prediction by network analysis of individual protein structures

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Positive selection on protein-length in the evolution of a primate sperm ion channel

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12 December 2020

Fast time scale dynamics of protein backbones: NMR relaxation methods, applications, and functional consequences

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Barley lipid-transfer protein complexed with palmitoyl CoA: the structure reveals a hydrophobic binding site that can expand to fit both large and small lipid-like ligands

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12 December 2020

Intrinsically unstructured proteins and their functions

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12 December 2020

Inactivation of the sodium channel. I. Sodium current experiments

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12 December 2020

The entropy cost of protein association

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12 December 2020

Effects of proline cis-trans isomerization on TB domain secondary structure

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12 December 2020

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

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12 December 2020

"New View" of Protein Folding Reconciled with the Old Through Multiple Unfolding Simulations

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12 December 2020

Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits*

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12 December 2020

A relationship between protein stability and protein function

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12 December 2020

Intrinsically unstructured proteins

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12 December 2020

10.1007/S00018-009-0014-6

Identifiers

DOI

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21 June 2017

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